Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial
JC Tardif, N Bouabdallaoui, PL L'allier… - The Lancet …, 2021 - thelancet.com
Background Evidence suggests a role for excessive inflammation in COVID-19
complications. Colchicine is an oral anti-inflammatory medication beneficial in gout …
complications. Colchicine is an oral anti-inflammatory medication beneficial in gout …
Efficacy of colchicine in non-hospitalized patients with COVID-19
JC Tardif, N Bouabdallaoui, PL L'Allier, D Gaudet… - Medrxiv, 2021 - medrxiv.org
Background Evidence suggests the role of an inflammatory storm in COVID-19
complications. Colchicine is an orally administered, anti-inflammatory medication beneficial …
complications. Colchicine is an orally administered, anti-inflammatory medication beneficial …
[HTML][HTML] Colchicine in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
RECOVERY Collaborative Group - The Lancet Respiratory Medicine, 2021 - Elsevier
Background Colchicine has been proposed as a treatment for COVID-19 based on its anti-
inflammatory actions. We aimed to evaluate the efficacy and safety of colchicine in patients …
inflammatory actions. We aimed to evaluate the efficacy and safety of colchicine in patients …
Beneficial effects of colchicine for moderate to severe COVID-19: a randomised, double-blinded, placebo-controlled clinical trial
MI Lopes, LP Bonjorno, MC Giannini, NB Amaral… - RMD open, 2021 - rmdopen.bmj.com
Objective To evaluate whether the addition of colchicine to standard treatment for COVID-19
results in better outcomes. Design We present the results of a randomised, double-blinded …
results in better outcomes. Design We present the results of a randomised, double-blinded …
Colchicine for COVID-19 in the community (PRINCIPLE): a randomised, controlled, adaptive platform trial
J Dorward, LM Yu, G Hayward, BR Saville… - British Journal of …, 2022 - bjgp.org
Background Colchicine has been proposed as a COVID-19 treatment. Aim To determine
whether colchicine reduces time to recovery and COVID-19-related admissions to hospital …
whether colchicine reduces time to recovery and COVID-19-related admissions to hospital …
Association between treatment with colchicine and improved survival in a single-centre cohort of adult hospitalised patients with COVID-19 pneumonia and acute …
M Scarsi, S Piantoni, E Colombo, P Airó… - Annals of the …, 2020 - ard.bmj.com
Objectives The outbreak of COVID-19 posed the issue of urgently identifying treatment
strategies. Colchicine was considered for this purpose based on well-recognised anti …
strategies. Colchicine was considered for this purpose based on well-recognised anti …
Colchicine in recently hospitalized patients with COVID-19: a randomized controlled trial (COL-COVID)
DA Pascual-Figal, AE Roura-Piloto… - … Journal of General …, 2021 - Taylor & Francis
Background Colchicine has been proposed as a potential therapy in coronavirus disease
2019 (COVID-19) due to their anti-inflammatory actions. Methods The COL-COVID study …
2019 (COVID-19) due to their anti-inflammatory actions. Methods The COL-COVID study …
Reduced mortality in COVID-19 patients treated with colchicine: Results from a retrospective, observational study
Objectives Effective treatments for coronavirus disease 2019 (COVID-19) are urgently
needed. We hypothesized that colchicine, by counteracting proinflammatory pathways …
needed. We hypothesized that colchicine, by counteracting proinflammatory pathways …
A case control study to evaluate the impact of colchicine on patients admitted to the hospital with moderate to severe COVID‐19 infection
T Sandhu, A Tieng, S Chilimuri… - Canadian Journal of …, 2020 - Wiley Online Library
Background. Colchicine has been used in conditions such as periodic febrile illness, acute
pericarditis, and gouty arthritis, all having a common hyperinflammatory response as seen in …
pericarditis, and gouty arthritis, all having a common hyperinflammatory response as seen in …
Colchicine as a potent anti-inflammatory treatment in COVID-19: can we teach an old dog new tricks?
S Deftereos, G Giannopoulos… - European Heart …, 2020 - academic.oup.com
The recent pandemic has called for urgent treatment solutions for severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2)-infected patients. Undeniably, the …
syndrome coronavirus-2 (SARS-CoV-2)-infected patients. Undeniably, the …