Gut microbiota in ulcerative colitis: insights on pathogenesis and treatment

XY Guo, XJ Liu, JY Hao - Journal of digestive diseases, 2020 - Wiley Online Library
Gut microbiota constitute the largest reservoir of the human microbiome and are an
abundant and stable ecosystem—based on its diversity, complexity, redundancy, and host …

[HTML][HTML] Fecal microbiota transplantation for inflammatory bowel disease

J Lopez, A Grinspan - Gastroenterology & hepatology, 2016 - ncbi.nlm.nih.gov
The gut bacterial microbiome, particularly its role in disease and inflammation, has gained
international attention with the successful use of fecal microbiota transplantation (FMT) in the …

Aetiology of inflammatory bowel disease (IBD): role of intestinal microbiota and gut-associated lymphoid tissue immune response

OC Thompson-Chagoyán, J Maldonado, A Gil - Clinical Nutrition, 2005 - Elsevier
The aetiology of inflammatory bowel disease (IBD) probably involves a combination of
genetic predisposition and environmental factors that may be channelled through an …

Step-up fecal microbiota transplantation (FMT) strategy

B Cui, P Li, L Xu, Z Peng, J Xiang, Z He, T Zhang… - Gut …, 2016 - Taylor & Francis
Gut dysbiosis is a characteristic of inflammatory bowel disease (IBD) and is believed to play
a role in the pathogenesis of IBD. Fecal microbiota transplantation (FMT) is an effective …

Defined microbiota transplant restores Th17/RORγt+ regulatory T cell balance in mice colonized with inflammatory bowel disease microbiotas

GJ Britton, EJ Contijoch, MP Spindler… - Proceedings of the …, 2020 - National Acad Sciences
The building evidence for the contribution of microbiota to human disease has spurred an
effort to develop therapies that target the gut microbiota. This is particularly evident in …

Fecal microbiota transplantation as new therapeutic avenue for human diseases

M Biazzo, G Deidda - Journal of Clinical Medicine, 2022 - mdpi.com
The human body is home to a variety of micro-organisms. Most of these microbial
communities reside in the gut and are referred to as gut microbiota. Over the last decades …

Antibiotic treatment induces long-lasting changes in the fecal microbiota that protect against colitis

NL Ward, CD Phillips, DD Nguyen… - Inflammatory bowel …, 2016 - academic.oup.com
Background The interplay between host genetics, immunity, and microbiota is central to the
pathogenesis of inflammatory bowel disease. Previous population-based studies suggested …

Efficacy, safety, and concerns on microbiota modulation, antibiotics, probiotics, and fecal microbial transplant for inflammatory bowel disease and other gastrointestinal …

TL Parigi, S Vieujean, K Paridaens, K Dalgaard… - Microorganisms, 2023 - mdpi.com
The gut microbiota play a pivotal role in human health. Dysbiosis, alterations in microbiota
composition and function, is associated with gastrointestinal disorders, including …

Bacteroides ovatus ATCC 8483 monotherapy is superior to traditional fecal transplant and multi-strain bacteriotherapy in a murine colitis model

FD Ihekweazu, TY Fofanova, K Queliza… - Gut …, 2019 - Taylor & Francis
Background and aims Bacteriotherapy aimed at addressing dysbiosis may be therapeutic for
Inflammatory Bowel Diseases (IBDs). We sought to determine if defined Bacteroides-based …

Transferable immunoglobulin A–Coated Odoribacter splanchnicus in responders to fecal microbiota transplantation for ulcerative colitis limits colonic inflammation

SF Lima, L Gogokhia, M Viladomiu, L Chou, G Putzel… - Gastroenterology, 2022 - Elsevier
Background & Aims Fecal microbiota transplantation (FMT) is an emerging treatment
modality for ulcerative colitis (UC). Several randomized controlled trials have shown efficacy …