Astrocytes sense, integrate, and respond to stimuli generated by neurons or neural injury;
this response involves gap junction (GJ) communication. Neuronal vulnerability to injury …

Abstract Sphingosine‐1‐phosphate (S1P) is a potent and pleiotropic bioactive
lysophospholipid mostly released by activated platelets that acts on its target cells through …

Several molecules have been shown to be involved in glial-neuronal communication,
including S100B, an astrocyte-derived neurotrophic cytokine. Extracellular S100B protects …

Astrocytes are the major glial cells in brain tissue and are involved, among many functions,
ionic and metabolic homeostasis maintenance of synapses. These cells express receptors …

Astrogliosis is a pathological process that affects the density, morphology, and function of
astrocytes. It is a common feature of brain trauma, autoimmune diseases, and …

S100B is the principal calcium-binding protein of astrocytes and known to be secreted to
extracellular space. Although secreted S100B has been reported to promote neurite …

1. S100B is a calcium-binding protein expressed and secreted by astrocytes, which has
been implicated in glial-neuronal communication. Extracellular S100B appears to protect …

Brain slices prepared from adult rats and maintained for up to 3 h in vitro were used to
investigate the effects of pharmacological treatments on the phosphorylation state …

S100B is a calcium-binding protein expressed and secreted by astrocytes, playing a
neurotrophic role in neighboring cells. A protective role of the S100B against glutamate …

Glial cells are traditionally regarded as elements for structural support and ionic
homeostasis, but have recently attracted attention as putative integral elements of the …