Studies of the impact of enteric pathogens and their virulence factors on the proteins
comprising the tight junction and zonula adherens offer a novel approach to dissection of …

[Frontiers in Bioscience 13, 7008-7021, May 1, 2008] 7008 Mechanisms of intestinal tight
junctional disruption during infection Page 1 [Frontiers in Bioscience 13, 7008-7021, May 1 …

The tight junctions are narrow belts that circumferentially surround the upper part of the
lateral surfaces of the adjacent epithelial cells to create fusion points or" kisses". They are …

The epithelial barrier is a critical border that segregates luminal material from entering
tissues. Essential components of this epithelial fence are physical intercellular structures …

The tight junction, or zonula occludens, forms an intercellular barrier between epithelial cells
within the gastrointestinal tract and liver and, by limiting the movement of water and solutes …

Physiol 279: G851–G857, 2000.—The epithelial lining of the gastrointestinal tract forms a
regulated, selectively permeable barrier between luminal contents and the underlying tissue …

Tight junction permeability differs with the type of permeants, their size, and their charge.
Selective changes in permeability do occur, and they illustrate the diversity in functional …

A variety of evidence suggests that specific parameters of tight-junction structure correlate
with tight-junction function. Thus, one potential indirect means of probing the functional …

Like all mucosal surfaces, the intestine forms a barrier that separates the external
environment, ie, the gut lumen, from the protected internal milieu. The intestinal barrier is …

The primary function of the gastrointestinal tract is to digest and absorb nutrients. To
accomplish this, it must maintain a barrier between the luminal environment, technically a …