Abstract NMDA (N-methyl-d-aspartate) receptors (NMDARs) play a central role in excitotoxic
neuronal death caused by ischemic stroke, but NMDAR channel blockers have failed to be …

Despite abundant evidence from basic/preclinical research that excessive NMDAR (N-
methyl-d-aspartate receptor) stimulation is a crucial step required for brain damage following …

Stroke is a leading cause of death and disability in developed countries. N-methyl-D-
aspartate glutamate receptors (NMDARs) have important roles in stroke pathology and …

N-methyl-D-aspartate receptors (NMDAR) have a recognized role in neuronal plasticity
while their excessive activation results in excitotoxic death. Therefore, NMDAR antagonists …

Well-documented experimental evidence from both in vitro and in vivo models of stroke
strongly supports the critical involvement of NMDA receptor-mediated excitotoxicity in …

Stroke and late-onset Alzheimer's disease (AD) are risk factors for each other; the
comorbidity of these brain disorders in aging individuals represents a significant challenge …

Background and Purpose—Glutamate NMDARs (N-methyl-d-aspartate receptors) play a
major role in the initiation of ischemic brain damage. However, NMDAR antagonists have no …

There is a long-standing paradox that NMDA (N-methyl-d-aspartate) receptors (NMDARs)
can both promote neuronal health and kill neurons. Recent studies show that NMDAR …

Excessive activation of NMDA glutamate receptors contributes to neuronal death after
stroke. In this issue, Tu et al.(2010) demonstrate that ischemic injury promotes the …

N-methyl-d-aspartate receptors (NMDARs) play an important role in cell survival versus cell
death decisions during neuronal development, ischemia, trauma, and epilepsy. Coupling of …