ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is having serious consequences on …
J Gao, S Hu - Bioscience trends, 2020 - jstage.jst.go.jp
Drugs that are specifically efficacious against SARS-CoV-2 have yet to be established. Chloroquine and hydroxychloroquine have garnered considerable attention for their …
Hydroxychloroquine, initially used as an antimalarial, is used as an immunomodulatory and anti-inflammatory agent for the management of autoimmune and rheumatic diseases such …
SA Meo, DC Klonoff, J Akram - European Review for …, 2020 - talkingaboutthescience.com
OBJECTIVE: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also called COVID-19, has caused a pandemic which has swiftly involved the entire world …
There are currently no proven or approved treatments for coronavirus disease 2019 (COVID‐ 19). Early anecdotal reports and limited in vitro data led to the significant uptake of …
N Sinha, G Balayla - Postgraduate medical journal, 2020 - academic.oup.com
Hydroxychloroquine and chloroquine are medications that have been used for a long time. Their most common use is for the treatment and prophylaxis of malaria. However, these …
In December 2019, the novel coronavirus disease pandemic (COVID-19) that began in China had infected so far more than 109,217,366 million individuals worldwide and …
K Gbinigie, K Frie - BJGP open, 2020 - bjgpopen.org
Background On the 11 March 2020, the World Health Organization (WHO) declared that COVID-19 was a pandemic. To date, there are no medical treatments for COVID-19 with …
There is a long trail of research studies testing the in vitro and in vivo efficacy of chloroquine and its derivatives in treating and preventing infection by various coronavirus species. More …