JM Starr, AJ Farrall, P Armitage, B McGurn… - Psychiatry Research …, 2009 - Elsevier
Blood-brain barrier (BBB) dysfunction may contribute to the risk of Alzheimer's disease (AD). Dynamic contrast-enhanced magnetic resonance imaging (MRI) was performed repeatedly …
To investigate whether blood–brain barrier (BBB) disruption is a potential mechanism of usual age-related cognitive decline, we conducted dynamic contrast–enhanced (DCE) MRI …
HJ Van De Haar, JFA Jansen, CR Jeukens… - Medical …, 2017 - Wiley Online Library
Purpose Dynamic contrast‐enhanced (DCE) MRI can be used to measure blood‐brain barrier (BBB) leakage. In neurodegenerative disorders such as small vessel disease and …
Objective Blood–brain barrier (BBB) breakdown has been suggested to be an early biomarker in human cognitive impairment. However, the relationship between BBB …
The neurovascular unit, which protects neuronal cells and supplies them with essential molecules, plays an important role in the pathophysiology of Alzheimer's Disease (AD). The …
Blood–brain barrier (BBB) breakdown can disrupt nutrient supply and waste removal, which affects neuronal functioning. Currently, dynamic contrast-enhanced (DCE) MRI is the …
M Li, Y Li, L Zuo, W Hu, T Jiang - BMC neurology, 2021 - Springer
Background Blood-brain barrier (BBB) breakdown, as an early biomarker for vascular mild cognitive impairment (vMCI), has only been validated by a few studies. The aim of this study …
AP Viggars, SB Wharton, JE Simpson, FE Matthews… - Neuroscience …, 2011 - Elsevier
Impairment of the blood brain barrier (BBB) in human brain ageing and its relationship to Alzheimer-type pathology remains poorly defined. We have investigated the BBB in …
Blood-brain barrier (BBB) leakage is considered an important underlying process in both cerebral small vessel disease (cSVD) and Alzheimer's disease (AD). The objective of this …