Microvessel-like structures from outgrowth endothelial cells from human peripheral blood in 2-dimensional and 3-dimensional co-cultures with osteoblastic lineage …

S Fuchs, A Hofmann, CJ Kirkpatrick - Tissue engineering, 2007 - liebertpub.com
Tissue regeneration involves complex processes in the interaction between different cell
types that control the process of neo-vascularization. In bone, osteoblasts and bone marrow …

Endothelial cells assemble into a 3-dimensional prevascular network in a bone tissue engineering construct

J Rouwkema, JD Boer, CAV Blitterswijk - Tissue engineering, 2006 - liebertpub.com
To engineer tissues with clinically relevant dimensions, one must overcome the challenge of
rapidly creating functional blood vessels to supply cells with oxygen and nutrients and to …

[PDF][PDF] Macrophage-mediated angiogenic activation of outgrowth endothelial cells in co-culture with primary osteoblasts

E Dohle, I Bischoff, T Böse, A Marsano, A Banfi… - Eur Cell …, 2014 - ecmjournal.org
The successful vascularisation of complex tissue engineered constructs for bone
regeneration is still a major challenge in the field of tissue engineering. In this context, co …

Outgrowth endothelial cells: sources, characteristics and potential applications in tissue engineering and regenerative medicine

S Fuchs, E Dohle, M Kolbe, CJ Kirkpatrick - Bioreactor Systems for Tissue …, 2010 - Springer
Endothelial progenitor cells from peripheral blood or cord blood are attracting increasing
interest as a potential cell source for cellular therapies aiming to enhance the …

Paracrine effects influenced by cell culture medium and consequences on microvessel-like structures in cocultures of mesenchymal stem cells and outgrowth …

M Kolbe, Z Xiang, E Dohle, M Tonak… - … Engineering Part A, 2011 - liebertpub.com
Mesenchymal stem cells (MSC) from bone marrow and outgrowth endothelial cells (OEC)
from peripheral blood are considered as attractive cell types for applications in regenerative …

Contribution of outgrowth endothelial cells from human peripheral blood on in vivo vascularization of bone tissue engineered constructs based on starch …

S Fuchs, S Ghanaati, C Orth, M Barbeck, M Kolbe… - Biomaterials, 2009 - Elsevier
In the present study we assessed the potential of human outgrowth endothelial cells (OEC),
a subpopulation within endothelial progenitor cell cultures, to support the vascularization of …

Improved Microvascular Network in Vitro by Human Blood Outgrowth Endothelial Cells Relative to Vessel-Derived Endothelial Cells

AL Sieminski, RP Hebbel, KJ Gooch - Tissue engineering, 2005 - liebertpub.com
Evidence suggests that bone marrow-derived cells circulating in adult blood, sometimes
called endothelial progenitor cells, contribute to neovascularization in vivo and give rise to …

The effect of human osteoblasts on proliferation and neo-vessel formation of human umbilical vein endothelial cells in a long-term 3D co-culture on polyurethane …

A Hofmann, U Ritz, S Verrier, D Eglin, M Alini, S Fuchs… - Biomaterials, 2008 - Elsevier
Angiogenesis is a key element in early wound healing and is considered important for tissue
regeneration and for directing inflammatory cells to the wound site. The improvement of …

Cell communication in a coculture system consisting of outgrowth endothelial cells and primary osteoblasts

DPE Herzog, E Dohle, I Bischoff… - BioMed research …, 2014 - Wiley Online Library
Bone tissue is a highly vascularized and dynamic system with a complex construction. In
order to develop a construct for implant purposes in bone tissue engineering, a proper …

Endothelial cells enhance the in vivo bone-forming ability of osteogenic cell sheets

RP Pirraco, T Iwata, T Yoshida, AP Marques… - Laboratory …, 2014 - nature.com
Addressing the problem of vascularization is of vital importance when engineering three-
dimensional (3D) tissues. Endothelial cells are increasingly used in tissue-engineered …