[HTML][HTML] Pancreatic stellate cells: a starring role in normal and diseased pancreas

MV Apte, RC Pirola, JS Wilson - Frontiers in physiology, 2012 - frontiersin.org
While the morphology and function of cells of the exocrine and endocrine pancreas have
been studied over several centuries, one important cell type in the gland, the pancreatic …

Pancreatic stellate cell: physiologic role, role in fibrosis and cancer

M Apte, RC Pirola, JS Wilson - Current opinion in …, 2015 - journals.lww.com
Improved understanding of the role of PSCs in pancreatic pathophysiology has prompted a
focus on translational studies aimed at developing novel approaches to modulate PSC …

[HTML][HTML] Pancreatic stellate cell: Pandora's box for pancreatic disease biology

RR Bynigeri, A Jakkampudi, R Jangala… - World journal of …, 2017 - ncbi.nlm.nih.gov
Pancreatic stellate cells (PSCs) were identified in the early 1980s, but received much
attention after 1998 when the methods to isolate and culture them from murine and human …

[HTML][HTML] The pancreatic stellate cell: a star on the rise in pancreatic diseases

MB Omary, A Lugea, AW Lowe… - The Journal of clinical …, 2007 - Am Soc Clin Investig
Pancreatic stellate cells (PaSCs) are myofibroblast-like cells found in the areas of the
pancreas that have exocrine function. PaSCs are regulated by autocrine and paracrine …

Pancreatic stellate cells–multi-functional cells in the pancreas

A Masamune, T Shimosegawa - Pancreatology, 2013 - Elsevier
There is accumulating evidence that activated pancreatic stellate cells (PSCs) play a pivotal
role in pancreatic fibrosis in chronic pancreatitis and pancreatic cancer. In addition, we have …

[HTML][HTML] Molecular mechanism of pancreatic stellate cells activation in chronic pancreatitis and pancreatic cancer

G Jin, W Hong, Y Guo, Y Bai, B Chen - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Activated pancreatic stellate cells (PSCs) are the main effector cells in the process of
fibrosis, a major pathological feature in pancreatic diseases that including chronic …

Key role of pancreatic stellate cells in pancreatic cancer

SP Pothula, Z Xu, D Goldstein, RC Pirola, JS Wilson… - Cancer letters, 2016 - Elsevier
Pancreatic stellate cells (PSCs) are responsible for producing the collagenous stroma in
pancreatic cancer. Findings from the majority of in vitro and in vivo studies to date indicate …

[HTML][HTML] Signal transduction in pancreatic stellate cells

A Masamune, T Shimosegawa - Journal of gastroenterology, 2009 - Springer
Pancreatic fibrosis is a characteristic feature of chronic pancreatitis and of desmoplastic
reaction associated with pancreatic cancer. For over a decade, there has been accumulating …

Roles of pancreatic stellate cells in pancreatic inflammation and fibrosis

A Masamune, T Watanabe, K Kikuta… - Clinical Gastroenterology …, 2009 - Elsevier
Over a decade, there is accumulating evidence that activated pancreatic stellate cells
(PSCs) play a pivotal role in the development of pancreatic fibrosis. In response to …

Isolation of quiescent human pancreatic stellate cells: a promising in vitro tool for studies of human pancreatic stellate cell biology

A Vonlaufen, PA Phillips, L Yang, Z Xu, E Fiala-Beer… - Pancreatology, 2010 - karger.com
Background: Pancreatic stellate cells (PSCs) play a critical role in pancreatic fibrosis. To
date, human PSC biology has been studied using cancer-or inflammation-associated (pre …