Interactive effects of apelin, renin–angiotensin system and nitric oxide in treatment of obesity-induced type 2 diabetes mellitus in male albino rats

MM Sabry, MM Mahmoud, HS Shoukry… - … of physiology and …, 2019 - Taylor & Francis
Apelin and its receptor (APJ) are involved in the regulation of a variety of pathophysiological
processes. We studied the effect of apelin treatment on obesity-induced type 2 diabetes …

The effects of apelin treatment on a rat model of type 2 diabetes

R Akcılar, S Turgut, V Caner, A Akcılar, C Ayada… - Advances in medical …, 2015 - Elsevier
Purpose Apelin is an adipokine that plays a role in the regulation of many biological
functions in mammals including the neuroendocrine, cardiovascular, immune systems …

Ameliorative effect of apelin on streptozotocin-induced diabetes and its associated cardiac hypertrophy

II Hegab - Alexandria journal of medicine, 2018 - ajol.info
Aim: Apelin, an adipocyte-derived factor, exhibited a number of cardioprotective properties;
however, its effect in diabetes which is a major risk factor for cardiovascular disease (CVD) …

[PDF][PDF] Effect of regular exercise-induced apelin on dyslipidemia of type 2 diabetic rats

F Kazemi, K Ebrahim, SZ Asl - Res Med, 2016 - pejouhesh.sbmu.ac.ir
Background: Recently the role of apelin in improvement of dislipidemia has been known.
The purpose of this study was to determine the effect of regular exercise-induced apelin on …

The effect of apelin-13 on pancreatic islet beta cell mass and myocardial fatty acid and glucose metabolism of experimental type 2 diabetic rats

J Feng, H Zhao, M Du, X Wu - Peptides, 2019 - Elsevier
Apelin, a new identified adipokine, and its G protein–coupled receptor named APJ are
widely expressed in various tissues. Apelin has been found to play important roles in the …

Atni-inflammation effect of 8-week aerobic training on apelin plasma concentration in diabetic male rats

F Kazemi, S Zahedi Asl - Iranian Journal of Diabetes and Metabolism, 2017 - ijdld.tums.ac.ir
Background: Recently the role of apelin in inflammation has been known. However, the
effect of exercise training-induced cytokine apelin in diabetes status hasn't been …

L‐carnitine improves metabolic disorders and regulates apelin and apelin receptor genes expression in adipose tissue in diabetic rats

N Ranjbar Kohan, MR Tabandeh, S Nazifi… - Physiological …, 2020 - Wiley Online Library
Apelin is a new adipocytokine that acts as an endogenous hormone in various tissues
through its receptor (APJ). This study aimed to investigate the effects of oral administration of …

Effects of exercise training on adipose tissue apelin expression in streptozotocin-nicotinamide induced diabetic rats

F Kazemi, S Zahediasl - Gene, 2018 - Elsevier
Apelin is an adipocyte-derived peptide that plays an important role in regulation of energy
homoeostasis and decrease of insulin resistance. We investigated the effects of exercise …

[HTML][HTML] The effect of aerobic exercise training on plasma apelin levels and pain threshold in T1DM rats

R Delavar, A Heidarianpour - Iranian Red Crescent Medical …, 2016 - ncbi.nlm.nih.gov
Background Diabetes mellitus (types 1 and 2) leads to secondary complications such as
neuropathy, which reduce a patient's quality of life. Apelin and its receptor, APJ, have been …

Apelin‑13 ameliorates metabolic and cardiovascular disorders in a rat model of type 2 diabetes with a high‑fat diet

M Li, H Fang, J Hu - Molecular medicine reports, 2018 - spandidos-publications.com
Apelin has been reported to be associated with multiple physiological processes in the
cardiovascular system. The aim of the present study was to investigate the effects of Apelin …