While tissue biopsy has for the longest time been the gold-standard in biomedicine,
precision/personalized medicine is making the shift toward liquid biopsies. Cell-free DNA …

Cell-free DNA (cfDNA) serves as a valuable biomarker for early disease detection and
monitoring. However, the use of cfDNA for analysis faces challenges owing to general low …

Cell-free circulating DNA (cfDNA) in plasma has gained global interest as a diagnostic
material for noninvasive prenatal testing and cancer diagnosis, or the so-called “liquid …

Objective In the present study, we investigated different simple and cost effective methods to
evaluate and validate cell free DNA (cfDNA) isolation. The ability of the QIAamp DNA Blood …

Programmed cell death, accidental cell degradation and active extrusion constantly lead to
the release of DNA fragments into human body fluids from virtually all cell and tissue types. It …

The study of cell-free DNA (cfDNA) is often challenging due to genomic DNA contamination,
low concentration, and high fragmentation. Therefore, it is important to optimize pre …

Background Liquid biopsy consists in the quantification and qualification of circulating cell-
free DNA (cfDNA) and tumor-derived DNA (ctDNA) for cancer recognition. Recently, the …

A liquid biopsy is a minimally invasive or non-invasive method to analyze a range of tumor
material in blood or other body fluids, including circulating tumor cells (CTCs), cell-free DNA …

The increasing knowledge of the molecular pathogenesis of cancer and the rapid
development of new molecular techniques are promoting the study of early molecular …

The analysis of cell-free DNA (cfDNA) as a sensitive biomarker for cancer diagnosis and
monitoring has resulted in a need for efficient and standardized cfDNA isolation. In this …