NF-κB comprises a family of five transcription factors that form distinct protein complexes, which bind to consensus DNA sequences at promoter regions of responsive genes …
Nuclear factor kappa B (NF-κB) is a family of inducible transcription factors found virtually ubiquitously in all cells. Since its discovery by Sen and Baltimore in 1986, much has been …
R Ravi, A Bedi - Drug resistance updates, 2004 - Elsevier
The nuclear factor of κB (NF-κB) family of heterodimeric transcription factors plays an instrumental role in immune, inflammatory, and stress responses. NF-κB induces the …
YR Puar, MK Shanmugam, L Fan, F Arfuso, G Sethi… - Biomedicines, 2018 - mdpi.com
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is responsible for the regulation of a large number of genes that are involved in important physiological …
The nuclear factor‐κB (NF‐κB) transcription factor family has been considered the central mediator of the inflammatory process and a key participant in innate and adaptive immune …
M Karin, Y Cao, FR Greten, ZW Li - Nature reviews cancer, 2002 - nature.com
Nuclear factor of κB (NF-κB) is a sequence-specific transcription factor that is known to be involved in the inflammatory and innate immune responses. Although the importance of NF …
G Xiao, J Fu - American journal of cancer research, 2011 - ncbi.nlm.nih.gov
Recent studies have clearly linked nuclear factor-kappaB (NF-κB), a transcription factor that plays a central role in regulating immune and inflammatory responses, to tumor …
In the 20 years since its discovery, research into the NF-κB (nuclear factor-κB) family of transcription factors has revealed an amazing diversity of functions. NF-κB proteins are …
ND Perkins - Trends in cell biology, 2004 - cell.com
A role for the NF-κB family of transcription factors as tumor promoters is firmly established. However, other data suggest that NF-κB can also inhibit tumor growth. Moreover, NF-κB …