Scalable dissolution-dynamic nuclear polarization with rapid transfer of a polarized solid

K Kouřil, H Kouřilová, S Bartram, MH Levitt… - Nature …, 2019 - nature.com
In dissolution-dynamic nuclear polarization, nuclear spins are hyperpolarized at cryogenic
temperatures using radicals and microwave irradiation. The hyperpolarized solid is …

A cryogen-consumption-free system for dynamic nuclear polarization at 9.4 T

M Baudin, B Vuichoud, A Bornet… - Journal of Magnetic …, 2018 - Elsevier
A novel system for dissolution dynamic nuclear polarization based on a cost-effective
“cryogen-free” magnet that can generate fields up to 9.4 T with a sample space that can …

Optimizing dissolution dynamic nuclear polarization

A Bornet, S Jannin - Journal of Magnetic Resonance, 2016 - Elsevier
This article is a short review of some of our recent developments in dissolution dynamic
nuclear polarization (d-DNP). We present the basic principles of d-DNP, and motivate our …

[HTML][HTML] An automated system for fast transfer and injection of hyperpolarized solutions

M Ceillier, O Cala, T El Daraï, SF Cousin… - Journal of Magnetic …, 2021 - Elsevier
Dissolution dynamic nuclear polarization (dDNP) has become a hyperpolarization method of
choice for enhancing nuclear magnetic resonance (NMR) signals. Nuclear spins are …

Recycling and imaging of nuclear singlet hyperpolarization

G Pileio, S Bowen, C Laustsen… - Journal of the …, 2013 - ACS Publications
The strong enhancement of NMR signals achieved by hyperpolarization decays, at best,
with a time constant of a few minutes. Here, we show that a combination of long-lived singlet …

Formulation and utilization of choline based samples for dissolution dynamic nuclear polarization

S Bowen, JH Ardenkjaer-Larsen - Journal of Magnetic Resonance, 2013 - Elsevier
Hyperpolarization by the dissolution dynamic nuclear polarization (DNP) technique permits
the generation of high spin polarization of solution state. However, sample formulation for …

Cross Polarization for Dissolution Dynamic Nuclear Polarization Experiments at Readily Accessible Temperatures 1.2 < T < 4.2 K

A Bornet, R Melzi, S Jannin… - Applied Magnetic …, 2012 - Springer
Cross polarization can provide significant enhancements with respect to direct polarization
of low-γ nuclei such as 13 C. Substantial gains in sample throughput (shorter polarization …

Sample formulations for dissolution dynamic nuclear polarization

T El Daraï, S Jannin - Chemical Physics Reviews, 2021 - pubs.aip.org
Hyperpolarization by dissolution dynamic nuclear polarization (dDNP) can boost magnetic
resonance sensitivity by several orders of magnitude. The method relies on the transfer of …

Generating highly polarized nuclear spins in solution using dynamic nuclear polarization

J Wolber, F Ellner, B Fridlund, A Gram… - Nuclear Instruments and …, 2004 - Elsevier
A method to generate strongly polarized nuclear spins in solution has been developed,
using Dynamic Nuclear Polarization (DNP) at a temperature of 1.2 K, and at a field of 3.354 …

A cryogen-free, semi-automated apparatus for bullet-dynamic nuclear polarization with improved resolution

K Kouřil, M Gramberg, M Jurkutat… - Magnetic …, 2021 - mr.copernicus.org
In dissolution-dynamic nuclear polarization, a hyperpolarized solid is dissolved with a jet of
hot solvent. The solution is then transferred to a secondary magnet, where spectra can be …