Establishment of a nonhuman primate model for development of vaccines and anti-viral drugs against COVID-19

Y ITOH - Translational and Regulatory Sciences, 2021 - jstage.jst.go.jp
COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and has continued to spread worldwide since late 2019 [1]. It was speculated that SARS …

Role of syrian hamsters and nonhuman primates in covid-19 research

DY Patil, S Mohandas, PD Yadav - Indian Journal of …, 2021 - indianjournals.com
SARS-CoV-2 pandemic has created serious public health issues claiming millions of human
lives worldwide. Few vaccines for the control of COVID-19 are now available under …

Approach for the study of COVID-19 infection and vaccine development using mice model: A narrative review

L Hansur, M Louisa, PE Wuyung - AIP Conference Proceedings, 2022 - pubs.aip.org
COVID-19 global pandemics have called for researchers to design a suitable non-primate
animal model as a tool for the study of pathogenesis, drug, and vaccine candidates. Studies …

Mouse study of combined DNA/protein COVID-19 vaccine to boost high levels of antibody and cell mediated immune responses

Q He, S Liu, Z Liang, S Lu, W Cun… - Emerging Microbes & …, 2023 - Taylor & Francis
Rapid development of effective vaccines against SARS-CoV-2 has been a major
achievement in the global effort of controlling the COVID-19 pandemic [1-5]. However, the …

Animal models of SARS-CoV-2 infection and mechanisms of COVID-19

S Cleary, S Pitchford, R Amison, R Carrington… - Authorea …, 2020 - authorea.com
The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 infections
has led to substantial unmet need for treatments, many of which will require testing in …

An Overview on Animal Models to Boost Preclinical Research in COVID 19

RN MR, M Godbole, BKM Goud - Journal of Pharmaceutical …, 2022 - pnrjournal.com
The current review was undertaken by collecting data through a thorough literature search in
PubMed and Google Scholar in order to identify the relevant English-language articles …

Protective efficacy of inactivated vaccine against SARS-CoV-2 infection in mice and non-human primates

YF Yao, ZJ Wang, RD Jiang, X Hu, HJ Zhang, YW Zhou… - Virologica Sinica, 2021 - Springer
The ongoing coronavirus disease 2019 (COVID-19) pandemic caused more than 96 million
infections and over 2 million deaths worldwide so far. However, there is no approved …

Introduction to COVID-19

N Bano, F Batool, MN Bin-Jumah - Alternative Medicine Interventions for …, 2021 - Springer
An association between the wholesale market of Wuhan and the coronavirus was reported
in primary reported cases. And the possible source of this virus in that market was supposed …

Current global vaccine and drug efforts against COVID-19: Pros and cons of bypassing animal trials

B Deb, H Shah, S Goel - Journal of biosciences, 2020 - Springer
COVID-19 has become one of the biggest health concern, along with huge economic
burden. With no clear remedies to treat the disease, doctors are repurposing drugs like …

Using in vivo animal models for studying SARS-CoV-2

CBP Da Costa, ACDM Cruz, JCQ Penha… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction The search for an animal model capable of reproducing the physiopathology of
the COVID-19, and also suitable for evaluating the efficacy and safety of new drugs has …