[HTML][HTML] A stochastic process based modular tool-box for simulating COVID-19 infection spread

SS Manathunga, IA Abeyagunawardena… - Informatics in Medicine …, 2022 - Elsevier
Background The novel coronavirus disease (COVID-19) culminated in a pandemic with
many countries affected in varying stages. We aimed to develop a simulation environment …

[HTML][HTML] Initiation of antiviral treatment in SARS‐CoV2: modeling viral dynamics and drug properties

DS Rosenbloom, P Zhao, V Sinha - CPT: pharmacometrics & …, 2020 - ncbi.nlm.nih.gov
As the coronavirus disease 2019 (COVID-19) pandemic has evolved, the search for
vaccines and treatments continues in earnest. This pandemic is causing sharp increases in …

Modeling the within-host dynamics of SARS-CoV-2 infection based on antiviral treatment

T Song, Y Wang, X Gu, S Qiao - Mathematics, 2023 - mdpi.com
The COVID-19 pandemic has highlighted the profound impact of the SARS-CoV-2 virus as a
significant threat to human health. There is an urgent need to develop a comprehensive …

[PDF][PDF] In-host Modelling of COVID-19 in Humans

EA Hernandez-Vargas, JX Velasco-Hernandez - researchgate.net
COVID-19 pandemic has underlined the impact of emergent pathogens as a major threat for
human 2 health. The development of quantitative approaches to advance comprehension of …

Modeling, Analysis and Physics Informed Neural Network approaches for studying the dynamics of COVID-19 involving human-human and human-pathogen …

L Nguyen, M Raissi, P Seshaiyer - Computational and Mathematical …, 2022 - degruyter.com
In this work, the dynamics of the spread of COVID-19 is considered in the presence of both
human-to-human transmission as well as environment-to-human transmission. Specifically …

Modelling SARS-CoV-2 dynamics: implications for therapy

KS Kim, K Ejima, Y Ito, S Iwanami, H Ohashi, Y Koizumi… - MedRxiv, 2020 - medrxiv.org
The scientific community is focussed on developing antiviral therapies to mitigate the
impacts of the ongoing novel coronavirus disease (COVID-19) outbreak. This will be …

Mechanistic modeling of the SARS-CoV-2 and immune system interplay unravels design principles for diverse clinicopathological outcomes

S Sahoo, K Hari, S Jhunjhunwala, MK Jolly - BioRxiv, 2020 - biorxiv.org
The disease caused by SARS-CoV-2 is a global pandemic that threatens to bring long-term
changes worldwide. Approximately 80% of infected patients are asymptomatic or have mild …

Control intervention strategies for within-host, between-host and their efficacy in the treatment, spread of COVID-19: A multi scale modeling approach

DB Prakash, DKK Vamsi, DB Rajesh… - Computational and …, 2020 - degruyter.com
The COVID-19 pandemic has resulted in more than 65.5 million infections and 15, 14,695
deaths in 212 countries over the last few months. Different drug intervention acting at …

Dynamic heterogeneity in COVID-19: Insights from a mathematical model

C Voutouri, CC Hardin, V Naranbhai, MR Nikmaneshi… - Plos one, 2024 - journals.plos.org
Critical illness, such as severe COVID-19, is heterogenous in presentation and treatment
response. However, it remains possible that clinical course may be influenced by dynamic …

Modeling and simulations of CoViD-19 molecular mechanism induced by cytokines storm during SARS-CoV2 infection

Z Yu, R Ellahi, A Nutini, A Sohail, SM Sait - Journal of molecular liquids, 2021 - Elsevier
It is highly desired to explore the interventions of COVID-19 for early treatment strategies.
Such interventions are still under consideration. A model is benchmarked research and …