Although inflammation has a physiological role, unrestrained inflammation can be
detrimental, causing tissue damage and disease. Under normal circumstances inflammation …

Docosahexaenoic acid (C22: 6 n-3, DHA) is the precursor of specialized pro-resolving lipid
mediators (SPMs), such as resolvin, protectin, and maresin families which have been …

The molecular basis for the beneficial impact of essential omega-3 fatty acids is of
considerable interest. Recently, novel mediators generated from eicosapentaenoic acid …

A novel genus of pro-resolving lipid mediators endogenously generated from omega-3
polyunsaturated fatty acids has been identified in exudates obtained during the resolution …

A new genus of specialized pro-resolving mediators (SPM) which include several families of
distinct local mediators (lipoxins, resolvins, protectins, and maresins) are actively involved in …

Acute inflammatory responses are host‐protective and normally self‐limited; these
responses can maintain cell homeostasis and promote defense against various infections …

The molecular basis for the beneficial impact of essential omega-3 (n− 3) FA remains of
interest. Recently, we identified novel mediators generated from eicosapentaenoic acid …

Inflammation is a defensive response to injury and infection, but excessive or inappropriate
inflammation contributes to a range of acute and chronic human diseases. Clinical …

The endogenous cellular and molecular mechanisms that control acute inflammation and its
resolution are of wide interest. Using self-resolving inflammatory exudates and lipidomics …

The critical role of inflammatory processes in health and disease has long been recognized,
1 yet the detailed molecular mechanisms and biological events that regulate the progression …