From circuits to behavior: a bridge too far?

M Carandini - Nature neuroscience, 2012 - nature.com
Neuroscience seeks to understand how neural circuits lead to behavior. However, the gap
between circuits and behavior is too wide. An intermediate level is one of neural …

Cognitive computational neuroscience

N Kriegeskorte, PK Douglas - Nature neuroscience, 2018 - nature.com
To learn how cognition is implemented in the brain, we must build computational models
that can perform cognitive tasks, and test such models with brain and behavioral …

Building the human brain

CK Machens - Science, 2012 - science.org
The human brain is exceedingly complex and studying it encompasses gathering
information across a range of levels, from molecular processes to behavior. The sheer …

[图书][B] Computational neuroscience: a comprehensive approach

J Feng - 2003 - taylorfrancis.com
How does the brain work? After a century of research, we still lack a coherent view of how
neurons process signals and control our activities. But as the field of computational …

Reverse engineering the mouse brain

DH O'Connor, D Huber, K Svoboda - Nature, 2009 - nature.com
Behaviour is governed by activity in highly structured neural circuits. Genetically targeted
sensors and switches facilitate measurement and manipulation of activity in vivo, linking …

The promise and perils of causal circuit manipulations

SBE Wolff, BP Ölveczky - Current opinion in neurobiology, 2018 - Elsevier
Highlights•Mechanistic understanding of the brain requires assigning functions to neural
modules.•New sophisticated tools for manipulating neural activity advance this …

Quantifying behavior to understand the brain

TD Pereira, JW Shaevitz, M Murthy - Nature neuroscience, 2020 - nature.com
Over the past years, numerous methods have emerged to automate the quantification of
animal behavior at a resolution not previously imaginable. This has opened up a new field of …

Architectures of neuronal circuits

L Luo - Science, 2021 - science.org
BACKGROUND The human brain contains about 100 billion neurons, each of which makes
thousands of synaptic connections. Although individual neurons can themselves be …

Neurons learn by predicting future activity

A Luczak, BL McNaughton, Y Kubo - Nature machine intelligence, 2022 - nature.com
Understanding how the brain learns may lead to machines with human-like intellectual
capacities. It was previously proposed that the brain may operate on the principle of …

The atoms of neural computation

G Marcus, A Marblestone, T Dean - Science, 2014 - science.org
The human cerebral cortex is central to a wide array of cognitive functions, from vision to
language, reasoning, decision-making, and motor control. Yet, nearly a century after the …