For the investigation of the interaction of nanoparticles with biomolecules, cells, organs, and
animal models there is a need for well-characterized nanoparticle suspensions. In this paper …

The aggregation state of NP has been a significant source of difficulty for assessing their
toxic activity and great efforts have been done to reduce aggregation of and/or to disperse …

Abstract Purpose Silica nanoparticles (SNPs) are increasingly used as drug delivery
systems (DDS) and for biomedical imaging. Therapeutic and diagnostic agents can be …

The size, surface charge and agglomeration state of nanoparticles under physiological
conditions are fundamental parameters to be determined prior to their application in …

Cell cultures form the basis of most biological assays conducted to assess the cytotoxicity of
nanomaterials. Since the molecular environment of nanoparticles exerts influence on their …

Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …

Background Many toxicological studies on silica nanoparticles (NPs) have been reported,
however, the literature often shows various conclusions concerning the same material. This …

Abstract Silica nanoparticles (SiO 2 NPs) have potential utility in controlled release. Despite
significant research in this area, there is a gap in the understanding of the correlation …

The development of safe engineered nanoparticles (NPs) requires a detailed understanding
of their interaction mechanisms on a cellular level. Therefore, quantification of NP …

Monodisperse spherical silica nanoparticles (SNPs) with diameters of 20–200 nm were
employed to study size, dose, and cell-type dependent cytotoxicity in A549 and HepG2 …