Direct oral anticoagulants: efficacy and safety in patient subgroups

TA Mavrakanas, C Samer, P Fontana, A Perrier - Swiss medical weekly, 2015 - smw.ch
Direct oral anticoagulants have recently emerged as an attractive choice for patients
requiring anticoagulation treatment. They have a rapid onset of action and can be …

Comparison of the effectiveness and safety of direct oral anticoagulants: a nationwide propensity score–weighted study

AB Ingason, JP Hreinsson, AS Agustsson… - Blood …, 2023 - ashpublications.org
In the pivotal randomized controlled trials (RCTs) for patients with atrial fibrillation, direct oral
anticoagulants (DOACs) had similar or even superior efficacy and safety compared with …

A practice tool for the new oral anticoagulants

A Massicotte - … Journal/Revue des Pharmaciens du Canada, 2014 - journals.sagepub.com
Although warfarin has been the “king” of oral anticoagulation for the past few decades, its
reign is now jeopardized by the recent marketing in Canada of 3 new oral anticoagulants …

Direct oral anticoagulants: a guide for daily practice

P Fontana, H Robert-Ebadi, H Bounameaux… - Swiss medical …, 2016 - smw.ch
In recent years, small oral compounds that specifically block activated coagulation factor X
(FXa) or thrombin (FIIa) have become alternatives to the anticoagulants that had been used …

Direct oral anticoagulants: new drugs and new concepts

JH Levy, AC Spyropoulos, CM Samama… - JACC: Cardiovascular …, 2014 - jacc.org
Direct oral anticoagulants (DOACs) are approved for multiple thromboembolic disorders and
provide advantages over existing agents. As with all anticoagulants, management protocols …

Oral anticoagulant therapy: practical aspects of management

ML Brigden - Postgraduate medicine, 1996 - Taylor & Francis
Preview The overall prescription of oral anticoagulants has steadily increased as important
randomized clinical trials have clarified various indications for therapy. However, a number …

Laboratory assessment of the anticoagulant activity of direct oral anticoagulants: a systematic review

BT Samuelson, A Cuker, DM Siegal, M Crowther… - Chest, 2017 - Elsevier
Background Direct oral anticoagulants (DOACs) are the treatment of choice for most patients
with atrial fibrillation and/or noncancer-associated venous thromboembolic disease …

New oral anticoagulants: dosing and monitoring

JP Patel, L Couchman, PB Chitongo… - BMJ: British Medical …, 2015 - search.proquest.com
New oral anticoagulants: dosing and monitoring Page 1 GASTROINTESTINAL BLEEDING
AND ORAL ANTICOAGULANTS New oral anticoagulants: dosing and monitoring Jignesh P …

Direct‐acting oral anticoagulants: pharmacology, indications, management, and future perspectives

A Gómez‐Outes, ML Suárez‐Gea… - European journal of …, 2015 - Wiley Online Library
In recent years, several direct‐acting oral anticoagulants (DOAC) have become available for
use in Europe and other regions in indications related to prophylaxis and treatment of …

Antidotes for the direct oral anticoagulants: What news?

S Galliazzo, MP Donadini, W Ageno - Thrombosis Research, 2018 - Elsevier
The direct oral anticoagulants (DOACs) are recommended as the first-choice anticoagulants
for both stroke prevention in patients with non-valvular atrial fibrillation and the treatment …