Mesenchymal stem cell (MSC)-derived exosomes as a cell-free therapy for patients Infected with COVID-19: Real opportunities and range of promises

L Rezakhani, AF Kelishadrokhi… - Chemistry and physics …, 2021 - Elsevier
There are no commercially available effective antiviral medications or vaccines to deal with
novel coronavirus disease (COVID-19). Hence there is a substantial unmet medical need for …

Nanomedicine to deliver biological macromolecules for treating COVID-19

B Wilson, KM Geetha - Vaccine, 2022 - Elsevier
Abstract Coronavirus disease (COVID-19) was first reported in December 2019, China and
later it was found that the causative microorganism is severe acute respiratory syndrome …

SARS-CoV-2 induced neurological manifestations entangles cytokine storm that implicates for therapeutic strategies

ZZ Chong, N Souayah - Current Medicinal Chemistry, 2022 - ingentaconnect.com
The new coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), can present neurological symptoms and induce …

Post COVID-19 complications, adjunct therapy explored, and steroidal after effects

C Sonkar, V Hase, D Banerjee, A Kumar… - Canadian Journal of …, 2022 - cdnsciencepub.com
For COVID-19 survivors, defeating the virus is just the beginning of a long road to recovery.
The inducibility and catastrophic effects of the virus are distributed across multiple organs …

[HTML][HTML] A step-by-step approach to improve clinical translation of liposome-based nanomaterials, a focus on innate immune and inflammatory responses

G Della Camera, D Lipsa, D Mehn, P Italiani… - International Journal of …, 2021 - mdpi.com
This study aims to provide guidelines to design and perform a robust and reliable physical-
chemical characterization of liposome-based nanomaterials, and to support method …

Inflammatory monocyte/macrophage modulation by liposome-entrapped spironolactone ameliorates acute lung injury in mice

WJ Ji, YQ Ma, X Zhang, L Zhang, YD Zhang… - …, 2016 - Taylor & Francis
Aim: To examine the therapeutic/preventive potential of liposome-encapsulated
spironolactone (SP; Lipo-SP) for acute lung injury (ALI) and fibrosis. Materials & methods …

Mesenchymal stem cells and their derived exosomes to combat Covid–19

M Yousefi Dehbidi, N Goodarzi… - Reviews in Medical …, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is causing an ongoing
pandemic of coronavirus disease 2019 (Covid‐19). Effective therapies are required for the …

[HTML][HTML] First recombinant high-density lipoprotein particles administration in a severe ICU COVID-19 patient, a multi-omics exploratory investigation

S Tanaka, F Begue, B Veeren, A Tran-Dinh, T Robert… - Biomedicines, 2022 - mdpi.com
High-density lipoproteins (HDLs) have multiple endothelioprotective properties. During
SARS-CoV-2 infection, HDL-cholesterol (HDL-C) concentration is markedly reduced, and …

[HTML][HTML] The big potential of small particles: lipid-based nanoparticles and exosomes in vaccination

MB Shimon, S Shapira, J Seni, N Arber - Vaccines, 2022 - mdpi.com
Some of the most significant medical achievements in recent history are the development of
distinct and effective vaccines, and the improvement of the efficacy of previously existing …

Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages

M Bartneck, FM Peters, KT Warzecha, M Bienert… - … , biology and medicine, 2014 - Elsevier
The encapsulation of drugs into liposomes aims to enhance their efficacy and reduce their
toxicity. Corticosteroid-loaded liposomes are currently being evaluated in patients suffering …