Olfactory dysfunction: a highly prevalent symptom of COVID-19 with public health significance

AR Sedaghat, I Gengler… - … –Head and Neck Surgery, 2020 - journals.sagepub.com
Objective Coronavirus disease 2019 (COVID-19) is a global pandemic affecting millions of
individuals, killing hundreds of thousands. Although typically described with characteristic …

SARS-CoV-2 receptors and entry genes are expressed in the human olfactory neuroepithelium and brain

L Fodoulian, J Tuberosa, D Rossier, M Boillat, C Kan… - Iscience, 2020 - cell.com
Reports indicate an association between COVID-19 and anosmia, as well as the presence
of SARS-CoV-2 virions in the olfactory bulb. To test whether the olfactory neuroepithelium …

Anosmia and COVID-19: perspectives on its association and the pathophysiological mechanisms involved

PR da Silva Júnior, ALOR Gomes, LEA Coelho… - The Egyptian Journal of …, 2021 - Springer
With the spread of SARS-CoV-2, contingency measures and plans to facilitate the screening
of infected patients are needed. Changes in olfaction have been cited as symptoms of the …

Neurological symptoms of COVID-19: the zonulin hypothesis

S Llorens, E Nava, M Muñoz-López… - Frontiers in …, 2021 - frontiersin.org
The irruption of SARS-CoV-2 during 2020 has been of pandemic proportions due to its rapid
spread and virulence. COVID-19 patients experience respiratory, digestive and neurological …

Recovery of anosmia in hamsters infected with SARS-CoV-2 is correlated with repair of the olfactory epithelium

RA Reyna, M Kishimoto-Urata, S Urata, T Makishima… - Scientific reports, 2022 - nature.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for a
pandemic affecting billions of people worldwide. Apart from the extreme global economic …

Anosmia: an evolution of our understanding of its importance in COVID-19 and what questions remain to be answered

S Saussez, JR Lechien, C Hopkins - European archives of oto-rhino …, 2021 - Springer
Background From the start of the pandemic, many European otolaryngologists observed an
unprecendented number of anosmic patients. Early reports proposed that anosmia could be …

[HTML][HTML] Gross and histopathology of COVID-19 with first histology report of olfactory bulb changes

GS Stoyanov, L Petkova, DL Dzhenkov… - Cureus, 2020 - ncbi.nlm.nih.gov
In nearly a year since the first reported cases of coronavirus disease 2019 (COVID-19),
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a lot has …

Pathophysiological relationship between COVID-19 and olfactory dysfunction: A systematic review

MH Las Casas Lima, ALB Cavalcante… - Brazilian Journal of …, 2022 - SciELO Brasil
Introduction SARS-CoV-2 is the pathogen of COVID-19. The virus is composed of the spike,
membrane and envelope. On physiological smell, odoriferous substances bind to proteins …

Infection mechanism of SARS-COV-2 and its implication on the nervous system

EE Reza-Zaldívar, MA Hernández-Sapiéns… - Frontiers in …, 2021 - frontiersin.org
In late December 2019, multiple atypical pneumonia cases resulted in severe acute
respiratory syndrome caused by a pathogen identified as a novel coronavirus SARS-CoV-2 …

Geographical variations in host predisposition to COVID-19 related anosmia, ageusia, and neurological syndromes

AA Kumar, SWY Lee, C Lock, NC Keong - Frontiers in medicine, 2021 - frontiersin.org
The novel coronavirus disease (COVID-19), has become the most critical global health
challenge in recent history. With SARS-CoV-2 infection, there was an unexpectedly high and …