COVID-19 and central nervous system interplay: A big picture beyond clinical manifestation

SS Chaudhury, K Sinha, R Majumder, A Biswas… - Journal of …, 2021 - Springer
Abstract The coronavirus disease (COVID-19) caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) has been declared a pandemic. Global research updates …

COVID-19-induced anosmia associated with olfactory bulb atrophy

A Chiu, N Fischbein, M Wintermark, G Zaharchuk… - Neuroradiology, 2021 - Springer
As the global COVID-19 pandemic evolves, our knowledge of the respiratory and non-
respiratory symptoms continues to grow. One such symptom, anosmia, may be a neurologic …

Co‑expression of peripheral olfactory receptors with SARS‑CoV‑2 infection mediators: Potential implications beyond loss of smell as a COVID‑19 symptom

R Kerslake, M Hall, HS Randeva… - International …, 2020 - spandidos-publications.com
Severe acute respiratory syndrome (SARS) coronavirus‑2 (SARS‑CoV‑2) enters into human
host cells via mechanisms facilitated mostly by angiotensin‑converting enzyme 2 (ACE2) …

Understanding the neurotropic characteristics of SARS-CoV-2: from neurological manifestations of COVID-19 to potential neurotropic mechanisms

Z Zhou, H Kang, S Li, X Zhao - Journal of neurology, 2020 - Springer
Abstract Coronavirus disease 2019 (COVID-19), a disease caused by the novel
betacoronavirus (SARS-CoV-2), has become a global pandemic threat. The potential …

[HTML][HTML] Olfactory bulb SARS‐CoV‐2 infection is not paralleled by the presence of virus in other central nervous system areas

G Lopez, C Tonello, G Osipova, L Carsana… - Neuropathology and …, 2022 - ncbi.nlm.nih.gov
The ongoing SARS-CoV-2 pandemic has proven to be challenging, in both clinical and
pathological terms. The viral tropism for angiotensinconverting enzyme 2 (ACE-2) receptor …

Olfactory dysfunction in COVID-19: pathology and long-term implications for brain health

RL Doty - Trends in Molecular Medicine, 2022 - cell.com
Decreased smell function is related to brain health, future mortality, and quality of life. Most
people inflicted with the SARS-CoV-2 virus evidence some measurable smell dysfunction …

Reduced T-cell densities in cranial nerves of patients who died with SARS-CoV-2 infection

J Bremer, J Friemann, S von Stillfried, P Boor… - Acta Neuropathologica …, 2023 - Springer
SARS-CoV-2 patients show a highly variable disease course, ranging from asymptomatic
infections to critical illness and death. Most of the fatalities occur in the older patient …

[HTML][HTML] Effects of COVID-19 on the nervous system

C Iadecola, J Anrather, H Kamel - Cell, 2020 - cell.com
Neurological complications have emerged as a significant cause of morbidity and mortality
in the ongoing COVID-19 pandemic. Beside respiratory insufficiency, many hospitalized …

The olfactory route is a potential way for SARS-CoV-2 to invade the central nervous system of rhesus monkeys

L Jiao, Y Yang, W Yu, Y Zhao, H Long, J Gao… - Signal transduction and …, 2021 - nature.com
Neurological manifestations are frequently reported in the COVID-19 patients.
Neuromechanism of SARS-CoV-2 remains to be elucidated. In this study, we explored the …

Olfactory gyrus intracerebral hemorrhage in a patient with COVID-19 infection

SS Thu, N Matin, SR Levine - Journal of Clinical Neuroscience, 2020 - Elsevier
Since the outbreak with novel corona virus in December 2019, a myriad of different
neurological manifestations in patients with COVID-19 infection have been reported. We …