Coronaviruses and central nervous system manifestations

M Khateb, N Bosak, M Muqary - Frontiers in Neurology, 2020 - frontiersin.org
SARS-CoV-2 is a highly pathogenic coronavirus that has caused an ongoing worldwide
pandemic. Emerging in Wuhan, China in December 2019, the virus has spread rapidly …

Is anosmia the price to pay in an immune-induced scorched-earth policy against COVID-19?

SD Le Bon, M Horoi - Medical hypotheses, 2020 - Elsevier
Since the outbreak of Coronavirus Disease 2019 (COVID-19), loss of smell has increasingly
been reported as a frequent clinical sign. Understanding the underlying mechanism and the …

Neurological aspects of SARS-CoV-2 infection: mechanisms and manifestations

P Guadarrama-Ortiz, JA Choreño-Parra… - Frontiers in …, 2020 - frontiersin.org
The human infection of the novel severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) is a public health emergency of international concern that has caused more than …

[HTML][HTML] Disruption of nuclear architecture as a cause of COVID-19 induced anosmia

M Zazhytska, A Kodra, DA Hoagland, JF Fullard… - BioRxiv, 2021 - ncbi.nlm.nih.gov
Olfaction relies on a coordinated partnership between odorant flow and neuronal
communication. Disruption in our ability to detect odors, or anosmia, has emerged as a …

Olfactory epithelium histopathological findings in long-term coronavirus disease 2019 related anosmia

LA Vaira, C Hopkins, A Sandison, A Manca… - The Journal of …, 2020 - cambridge.org
BackgroundOlfactory dysfunction represents one of the most frequent symptoms of
coronavirus disease 2019, affecting about 70 per cent of patients. However, the …

Emerging neurotropic features of SARS-CoV-2

WR Zhan, J Huang, PM Zeng, WY Tian… - Journal of Molecular …, 2021 - academic.oup.com
The prevailing coronavirus disease-19 (COVID-19) caused by a novel severe acute
respiratory syndrome coronavirus (SARS-CoV-2) has presented some neurological …

COVID-19-associated neurological manifestations: an emerging electroencephalographic literature

G Vellieux, R Sonneville, S Vledouts, P Jaquet… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide
since the end of year 2019 and is currently responsive for coronavirus infectious disease …

More that ACE2? NRP1 may play a central role in the underlying pathophysiological mechanism of olfactory dysfunction in COVID-19 and its association with …

C Hopkins, JR Lechien, S Saussez - Medical hypotheses, 2021 - Elsevier
Three mechanisms have been proposed to account for COVID-19 associated olfactory
dysfunction; obstruction of the olfactory cleft; epithelial injury and infection of the …

SARS-CoV-2: olfaction, brain infection, and the urgent need for clinical samples allowing earlier virus detection

R Butowt, K Bilinska - ACS chemical neuroscience, 2020 - ACS Publications
The novel SARS-CoV-2 virus has very high infectivity, which allows it to spread rapidly
around the world. Attempts at slowing the pandemic at this stage depend on the number and …

SARS-CoV-2 infection in the central and peripheral nervous system-associated morbidities and their potential mechanism

MKM Karuppan, D Devadoss, M Nair, HS Chand… - Molecular …, 2021 - Springer
The recent outbreak of SARS-CoV-2 infections that causes coronavirus-induced disease of
2019 (COVID-19) is the defining and unprecedented global health crisis of our time in both …