Upregulated circular RNA circ_0030235 predicts unfavorable prognosis in pancreatic ductal adenocarcinoma and facilitates cell progression by sponging miR-1253 …

Y Xu, Y Yao, P Gao, Y Cui - Biochemical and biophysical research …, 2019 - Elsevier
Accumulating evidence indicated that dysregulated circular RNAs (circRNAs) could play
pivotal roles in cancer biology. A recent study demonstrated that circ_0030235 expression is …

[HTML][HTML] CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m6A-modified CREB1 mRNA

B Yao, Q Zhang, Z Yang, F An, H Nie, H Wang, C Yang… - Molecular cancer, 2022 - Springer
Background Aberrant expression of circular RNAs (circRNAs) contributes to the initiation
and progression of human malignancies, but the underlying mechanisms remain largely …

circEPSTI1 regulates ovarian cancer progression via decoying miR‐942

J Xie, S Wang, G Li, X Zhao, F Jiang… - Journal of cellular …, 2019 - Wiley Online Library
Increasing studies show that circular RNAs (circRNAs) play vital roles in tumour progression.
But, how circRNAs function in ovarian cancer is mostly unclear. Here, we detected the …

[HTML][HTML] Circular RNA circDLC1 inhibits MMP1-mediated liver cancer progression via interaction with HuR

H Liu, T Lan, H Li, L Xu, X Chen, H Liao, X Chen… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: circular RNAs (circRNAs) have been demonstrated to play a crucial role in cancer
progression. KIAA1429, a key component of the m6A methyltransferase complex, has …

circKDM4C suppresses tumor progression and attenuates doxorubicin resistance by regulating miR-548p/PBLD axis in breast cancer

Y Liang, X Song, Y Li, P Su, D Han, T Ma, R Guo… - Oncogene, 2019 - nature.com
Increasing evidence has indicated that circular RNAs (circRNAs) play a critical role in cancer
development. However, only a small number of circRNAs have been experimentally …

[HTML][HTML] Circular noncoding RNA circMBOAT2 is a novel tumor marker and regulates proliferation/migration by sponging miR-519d-3p in colorectal cancer

X Tang, G Sun, Q He, C Wang, J Shi, L Gao, J Ye… - Cell death & …, 2020 - nature.com
Colorectal cancer (CRC) is a common malignant tumor with a poor prognosis. However, its
pathogenesis has not been fully elucidated, accounting for poor overall survival. Circular …

[HTML][HTML] ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner

C Zhang, Z Yu, S Yang, Y Liu, J Song, J Mao, M Li… - Molecular Cancer, 2024 - Springer
Abstract Background Circular RNAs are highly stable regulatory RNAs that have been
increasingly associated with tumorigenesis and progression. However, the role of many …

circSETD3 regulates MAPRE1 through miR-615-5p and miR-1538 sponges to promote migration and invasion in nasopharyngeal carcinoma

L Tang, W Xiong, L Zhang, D Wang, Y Wang, Y Wu… - Oncogene, 2021 - nature.com
Circular RNAs (circRNAs) play an essential role in tumorigenesis and development.
However, they have rarely been investigated in nasopharyngeal carcinoma (NPC). This …

[HTML][HTML] Circular RNA circRGNEF promotes bladder cancer progression via miR-548/KIF2C axis regulation

C Yang, Q Li, X Chen, Z Zhang, Z Mou, F Ye… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) play an important role in bladder cancer (BC). Though circRNA
involvement in BC has been reported, the underlying regulatory mechanisms are unknown …

[HTML][HTML] Role of a novel circRNA-CGNL1 in regulating pancreatic cancer progression via NUDT4–HDAC4–RUNX2–GAMT-mediated apoptosis

H Yuan, C Chen, H Li, G Qu, L Chen, Y Liu, Y Zhang… - Molecular Cancer, 2024 - Springer
Background Pancreatic cancer (PC) is an extremely malignant tumor with low survival rate.
Effective biomarkers and therapeutic targets for PC are lacking. The roles of circular RNAs …