Early high-titer plasma therapy to prevent severe Covid-19 in older adults

R Libster, G Pérez Marc, D Wappner… - … England Journal of …, 2021 - Mass Medical Soc
Background Therapies to interrupt the progression of early coronavirus disease 2019 (Covid-
19) remain elusive. Among them, convalescent plasma administered to hospitalized patients …

Early convalescent plasma for high-risk outpatients with Covid-19

FK Korley, V Durkalski-Mauldin… - … England Journal of …, 2021 - Mass Medical Soc
Background Early administration of convalescent plasma obtained from blood donors who
have recovered from coronavirus disease 2019 (Covid-19) may prevent disease …

[HTML][HTML] Randomized controlled trial of early outpatient COVID-19 treatment with high-titer convalescent plasma

DJ Sullivan, KA Gebo, S Shoham, EM Bloch, B Lau… - Medrxiv, 2021 - ncbi.nlm.nih.gov
BACKGROUND: The efficacy of polyclonal high titer convalescent plasma to prevent serious
complications of COVID-19 in outpatients with recent onset of illness is uncertain …

Convalescent plasma for COVID-19. A randomized clinical trial

A Gharbharan, CCE Jordans, C Geurtsvankessel… - MEDRxiv, 2020 - medrxiv.org
Structured abstract for full paper Background After recovery from COVID-19, most patients
have anti-SARS-CoV-2 neutralizing antibodies. Their convalescent plasma could be an …

Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection

A Gharbharan, CCE Jordans… - Nature …, 2021 - nature.com
In a randomized clinical trial of 86 hospitalized COVID-19 patients comparing standard care
to treatment with 300mL convalescent plasma containing high titers of neutralizing SARS …

Convalescent plasma therapy for COVID-19: a systematic review and meta-analysis on randomized controlled trials

C Filippatos, I Ntanasis-Stathopoulos, K Sekeri… - Viruses, 2023 - mdpi.com
Background: While passive immunotherapy has been considered beneficial for patients with
severe respiratory viral infections, the treatment of COVID-19 cases with convalescent …

Early outpatient treatment for Covid-19 with convalescent plasma

DJ Sullivan, KA Gebo, S Shoham… - … England Journal of …, 2022 - Mass Medical Soc
Background Polyclonal convalescent plasma may be obtained from donors who have
recovered from coronavirus disease 2019 (Covid-19). The efficacy of this plasma in …

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group, PW Horby… - MedRxiv, 2021 - medrxiv.org
Background Treatment of COVID-19 patients with plasma containing anti-SARS-CoV-2
antibodies may have a beneficial effect on clinical outcomes. We aimed to evaluate the …

Early high antibody titre convalescent plasma for hospitalised COVID-19 patients: DAWn-plasma

T Devos, Q Van Thillo, V Compernolle… - European …, 2022 - Eur Respiratory Soc
Background Several randomised clinical trials have studied convalescent plasma for
coronavirus disease 2019 (COVID-19) using different protocols, with different severe acute …

Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

P Bégin, J Callum, E Jamula, R Cook, NM Heddle… - Nature medicine, 2021 - nature.com
The efficacy of convalescent plasma for coronavirus disease 2019 (COVID-19) is unclear.
Although most randomized controlled trials have shown negative results, uncontrolled …