SARS-CoV-2 variants: A double-edged sword?

MP Jogalekar, A Veerabathini… - … Biology and Medicine, 2021 - journals.sagepub.com
Since the worldwide emergence of the COVID-19 outbreak, there have been international
concerns about the possible viral evolution into variants with underlying mutations that may …

The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

[HTML][HTML] SARS-CoV-2 variants–evolution, spike protein, and vaccines

KWK Chen, DTN Huang, LM Huang - biomedical journal, 2022 - Elsevier
Abstracts Despite the rising natural and vaccines mediated immunity, several countries have
experienced a resurgence of the Coronavirus disease of 2019 (COVID-19) due to the …

Molecular variants of SARS-CoV-2: antigenic properties and current vaccine efficacy

A Rayati Damavandi, R Dowran, S Al Sharif… - Medical Microbiology …, 2022 - Springer
An ongoing pandemic of newly emerged SARS-CoV-2 has puzzled many scientists and
health care policymakers around the globe. The appearance of the virus was accompanied …

SARS-CoV-2 variants and their relevant mutational profiles: update summer 2021

M Alkhatib, V Svicher, R Salpini… - Microbiology …, 2021 - Am Soc Microbiol
Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic caused by it,
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been undergoing a …

Epidemiology and characteristics of SARS-CoV-2 variants of concern: the impacts of the spike mutations

T Cocherie, K Zafilaza, V Leducq, S Marot, V Calvez… - Microorganisms, 2022 - mdpi.com
SARS-CoV-2 expresses on its surface the Spike protein responsible for binding with the
ACE2 receptor and which carries the majority of immunodominant epitopes. Mutations …

Emerging SARS-CoV-2 variants: genetic variability and clinical implications

A Dubey, S Choudhary, P Kumar, S Tomar - Current microbiology, 2022 - Springer
The sudden rise in COVID-19 cases in 2020 and the incessant emergence of fast-spreading
variants have created an alarming situation worldwide. Besides the continuous …

COVID-19 genetic variants and their potential impact in vaccine development

GV Vo, E Bagyinszky, SSA An - Microorganisms, 2022 - mdpi.com
In the two years since the SARS-CoV-2 pandemic started, it has caused over 5 million
deaths and 400 million infected cases, and the world continues to be on high alert for COVID …

[HTML][HTML] Mutations in SARS-CoV-2: Insights on structure, variants, vaccines, and biomedical interventions

AI Abulsoud, HM El-Husseiny, AA El-Husseiny… - Biomedicine & …, 2023 - Elsevier
COVID-19 is a worldwide pandemic caused by SARS-coronavirus-2 (SARS-CoV-2). Less
than a year after the emergence of the Covid-19 pandemic, many vaccines have arrived on …

[HTML][HTML] SARS-CoV-2 variants, spike mutations and immune escape

WT Harvey, AM Carabelli, B Jackson… - Nature Reviews …, 2021 - nature.com
Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …