Vascular endothelial damage in the pathogenesis of organ injury in severe COVID-19

A Dupont, A Rauch, S Staessens… - … and Vascular Biology, 2021 - Am Heart Assoc
Objective: Whether endotheliopathy only mirrors coronavirus disease 2019 (COVID-19)
severity or plays an intrinsic role in microvascular thrombosis and organ failure remains …

COVID-19 and fat embolism: a hypothesis to explain the severe clinical outcome in people with obesity

S Cinti, L Graciotti, A Giordano, A Valerio… - International Journal of …, 2020 - nature.com
As the number of confirmed cases of COVID-19 surges past 4.7 million globally and deaths
surpass 315,000, clinicians and pathologists are untiringly working to comprehend the …

[HTML][HTML] Endothelial dysfunction in COVID-19: Current findings and therapeutic implications

MP Nägele, B Haubner, FC Tanner, F Ruschitzka… - Atherosclerosis, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) increases the risk of several non-pulmonary
complications such as acute myocardial injury, renal failure or thromboembolic events. A …

Endothelial Dysfunction, Inflammation, and Oxidative Stress in COVID‐19—Mechanisms and Therapeutic Targets

A Fodor, B Tiperciuc, C Login… - Oxidative medicine …, 2021 - Wiley Online Library
The outbreak of the COVID‐19 pandemic represents an ongoing healthcare emergency
responsible for more than 3.4 million deaths worldwide. COVID‐19 is the disease caused by …

Pathophysiological association of endothelial dysfunction with fatal outcome in COVID-19

T Maruhashi, Y Higashi - International Journal of Molecular Sciences, 2021 - mdpi.com
The outbreak of coronavirus disease 2019 (COVID-19) caused by the betacoronavirus
SARS-CoV-2 is now a worldwide challenge for healthcare systems. Although the leading …

Obesity, diabetes, non-alcoholic fatty liver disease and metabolic dysfunction associated fatty liver disease are proinflammatory hypercoagulable states associated …

D Ji, M Zhang, E Qin, L Zhang, J Xu… - Metabolism …, 2021 - metabolismjournal.com
[1] Palaiodimos L, Kokkinidis DG, Li W, Karamanis D, Ognibene J, Arora S, et al. Severe
obesity, increasing age and male sex are independently associated with worse inhospital …

[HTML][HTML] Endothelial contribution to COVID-19: an update on mechanisms and therapeutic implications

Z Ma, KY Yang, Y Huang, KO Lui - Journal of Molecular and Cellular …, 2022 - Elsevier
The global propagation of SARS-CoV-2 leads to an unprecedented public health
emergency. Despite that the lungs are the primary organ targeted by COVID-19, systemic …

Pathogenic basis of thromboinflammation and endothelial injury in COVID-19: current findings and therapeutic implications

Y Higashikuni, W Liu, T Obana, M Sata - International Journal of …, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has become a global pandemic with a great impact on social …

Endothelial dysfunction and SARS-CoV-2 infection: association and therapeutic strategies

H Deng, TX Tang, D Chen, LS Tang, XP Yang… - Pathogens, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV-2), has been recently considered a systemic disorder leading to …

Plasma endothelial and oxidative stress biomarkers associated with late mortality in hospitalized COVID-19 patients

A Orea-Tejada, C Sánchez-Moreno… - Journal of Clinical …, 2022 - mdpi.com
Background: Coronavirus infectious disease 2019 (COVID-19) is a significant public health
problem worldwide. COVID-19 increases the risk of non-pulmonary complications such as …