GDF-15 predicts in-hospital mortality of critically ill patients with acute kidney injury requiring continuous renal replacement therapy: a multicenter prospective study

JH Lim, Y Jeon, JS Ahn, S Kim, DK Kim, JP Lee… - Journal of Clinical …, 2021 - mdpi.com
Growth differentiation factor-15 (GDF-15) is a stress-responsive cytokine. This study
evaluated the association between GDF-15 and in-hospital mortality among patients with …

Elevated serum GDF15 level as an early indicator of proximal tubular cell injury in acute kidney injury

T Sawasawa, JD Lin, YH Wang, KJ Chen, YM Yang… - Life Sciences, 2024 - Elsevier
Acute kidney injury (AKI) is a high-burden medical condition, and current diagnostic criteria
can only assess AKI after full manifestation. Stress marker growth differentiation factor 15 …

Growth differentiation factor‐15 is a predictor of mortality in critically ill patients with sepsis

L Buendgens, E Yagmur, J Bruensing… - Disease …, 2017 - Wiley Online Library
Growth differentiation factor‐15 (GDF‐15) is a member of the transforming growth factor‐β
superfamily related to inflammation and macrophage activation. Serum concentrations of …

Prognostic Value of GDF‐15 in Predicting Prolonged Intensive Care Stay following Cardiac Surgery: A Pilot Study

H Barton, E Zechendorf, D Ostareck… - Disease …, 2021 - Wiley Online Library
Introduction. Predicting intensive care unit length of stay and outcome following cardiac
surgery is currently based on clinical parameters. Novel biomarkers could be employed to …

GDF11 improves ischemia-reperfusion-induced acute kidney injury via regulating macrophage M1/M2 polarization

W Liu, L Feng, X Wang, L Wei, H Zou - Kidney and Blood Pressure …, 2023 - karger.com
Introduction: Acute kidney injury (AKI) is a clinical emergency caused by the rapid decline of
renal function caused by various etiologies. Growth differentiation factor 11 (GDF11) can …

Prognostic value of growth differentiation factor 15 in kidney donors and recipients

U Jehn, K Schütte-Nütgen, U Henke, J Bautz… - Journal of Clinical …, 2020 - mdpi.com
Growth differentiation factor-15 (GDF15) is associated with inflammatory conditions, chronic
kidney disease, cardiovascular disease and mortality. There is very limited data on GDF15 …

Growth differentiation factor 15: a biomarker with high clinical potential in the evaluation of kidney transplant candidates

M de Cos Gomez, A Benito Hernandez… - Journal of Clinical …, 2020 - mdpi.com
Kidney transplantation implies a significant improvement in patient survival. Nevertheless,
early mortality after transplant remains high. Growth differentiation factor 15 (GDF-15) is a …

GDF-15: a novel biomarker of heart failure predicts 30-day all-cause mortality and 30-day HF rehospitalization in patients with acute heart failure syndrome

P Kosum, N Mattanapojanat, N Siranart… - 2023 - researchsquare.com
Background: Growth Differentiation Factor-15 (GDF-15) is a distant member of the
transforming growth factor-β. The increased expression of GDF-15 has been observed …

Serum growth differentiation factor-15 analysis as a malnutrition marker inhemodialysis patients

D Turgut, DI Topcu, CC Alperen… - Turkish Journal of …, 2021 - journals.tubitak.gov.tr
Background/aim: Growth differentiation factor (GDF)-15 is related to inflammation and
mortality in many conditions. We aimed to determine if an elevated serum GDF-15 level is …

Growth differentiation factor-15 deficiency augments inflammatory response and exacerbates septic heart and renal injury induced by lipopolysaccharide

P Abulizi, N Loganathan, D Zhao, T Mele, Y Zhang… - Scientific reports, 2017 - nature.com
Septic acute kidney injury (AKI) and myocardial dysfunction are leading causes of mortality
with no accepted method of therapy. In this study we demonstrate the role of growth …