Walking a fine germline: Synthesizing public opinion and legal precedent to develop policy recommendations for heritable gene-editing

S Benston - Journal of Bioethical Inquiry, 2022 - Springer
Gene-editing technologies, such as CRISPR/Cas9, are internationally ethically fraught. In
the United States, policy surrounding gene-editing has yet to be implemented, while the …

Public and stakeholder engagement in developing human heritable genome editing policies: what does it mean and what should it mean?

AS Iltis, S Hoover, KRW Matthews - Frontiers in Political Science, 2021 - frontiersin.org
As scientific research pushes the boundaries of knowledge, new discoveries and
technologies often raise ethical and social questions. Public responses vary from surprise, to …

Shaping the CRISPR gene-editing debate: Questions about enhancement and germline modification

J Johnston - Perspectives in Biology and Medicine, 2020 - muse.jhu.edu
Today's debate about the use of gene-editing technologies to alter human DNA brings
together two longstanding lines of inquiry in bioethics: the ethics of human enhancement …

[PDF][PDF] Rewriting the human genome, rewriting human rights law? Human rights, human dignity, and human germline modification in the CRISPR era

BC Van Beers - Journal of Law and the Biosciences, 2020 - academic.oup.com
In most legal orders, human germline modification is either prohibited or severely restricted.
A recurring thought in these legal frameworks is that heritable genome editing would result …

Societal and ethical impacts of germline genome editing: How can we secure human rights?

J Halpern, SE O'Hara, KW Doxzen… - The CRISPR …, 2019 - liebertpub.com
Genome editing has opened up the possibility of heritable alteration of the human germline.
The potential of this powerful tool has spurred a call for establishing robust regulatory …

Editing the gene editing debate: Reassessing the normative discussions on emerging genetic technologies

O Feeney - NanoEthics, 2019 - Springer
The revolutionary potential of the CRISPR-Cas9 gene editing technique has created a
resurgence in enthusiasm and concern in genetic research perhaps not seen since the …

Realigning gene editing with clinical research ethics: what the “CRISPR Twins” debacle means for Chinese and international research ethics governance

E Kleiderman, U Ogbogu - Accountability in research, 2019 - Taylor & Francis
The announcement of the “CRISPR babies” reignited the debate surrounding the ethical,
legal and social implications of germline gene editing. Despite having been conducted in …

Cutting edges and weaving threads in the gene editing (Я) evolution: reconciling scientific progress with legal, ethical, and social concerns

A Nordberg, T Minssen, S Holm, M Horst… - Journal of Law and …, 2018 - academic.oup.com
Gene-editing technology, such as CRISPR/Cas9, holds great promise for the advancement
of science and many useful applications technology. This foundational technology enables …

Limits of Responsibility: Genome Editing, Asilomar, and the Politics of Deliberation

JB Hurlbut - Hastings Center Report, 2015 - Wiley Online Library
Abstract On April 3, 2015, a group of prominent biologists and ethicists called for a
worldwide moratorium on human genetic engineering in which the genetic modifications …

Do CRISPR germline ethics statements cut it?

C Brokowski - The CRISPR journal, 2018 - liebertpub.com
The extraordinary wave of genomic-engineering innovation, driven by CRISPR-Cas9, has
sparked worldwide scientific and ethical uncertainty. Great concern has arisen across the …