The role of fibrinogen as a cofactor for platelet aggregation was examined by measuring the
binding of 125I-labeled human fibrinogen to gel-filtered human platelets both before and …

The capacity of epinephrine alone and the combination of low dose epinephrine and ADP to
support the binding of fibrinogen to washed human platelets has been examined, 125I …

Fibrinogen is essential for aggregating platelets with adenosine diphosphate (ADP) and was
recently shown to bind to platelets stimulated with ADP. The present work confirms the …

Exposure of fibrinogen receptors by a variety of agonists is a prerequisite for platelet
aggregation. Because the synthesis of prostaglandins and thromboxane A2 also occurs …

Fibrinogen binding to receptors on stimulated platelets is a prerequisite for platelet
aggregation. To gain further insight into the role of fibrinogen in platelet aggregation and to …

The influence of divalent ions and ADP on the induction, relaxation, and stability of the ADP-
induced platelet receptor for fibrinogen was investigated. Platelets, isolated by differential …

To define better the role of the fibrinogen receptor in platelet physiology and to characterize
it biochemically, a murine monoclonal antibody that completely blocks the binding of …

ADP-induced platelet aggregation is associated with the specific binding of fibrinogen to
receptors. Since fibrinogen is also a cofactor for the spontaneous aggregation of chilled …

Fibrinogen binding to platelet plasma membranes, which is a prerequisite for platelet
aggregation, was determined by incubating 125I-labeled fibrinogen with isolated …

The role of fibrinogen as a cofactor in platelet aggregation is mediated by its binding to
platelet receptors that are induced by stimuli such as ADP. In the present study, we …