Genetic analyses support the contribution of mRNA N6-methyladenosine (m6A) modification to human disease heritability
Abstract N 6-methyladenosine (m6A) plays important roles in regulating messenger RNA
processing. Despite rapid progress in this field, little is known about the genetic …
processing. Despite rapid progress in this field, little is known about the genetic …
The RNA N6-methyladenosine modification landscape of human fetal tissues
S Xiao, S Cao, Q Huang, L Xia, M Deng, M Yang… - Nature cell …, 2019 - nature.com
A single genome gives rise to diverse tissues through complex epigenomic mechanisms,
including N 6-methyladenosine (m6A), a widespread RNA modification that is implicated in …
including N 6-methyladenosine (m6A), a widespread RNA modification that is implicated in …
m6A-LAIC-seq reveals the census and complexity of the m6A epitranscriptome
Abstract N 6-Methyladenosine (m6A) is a widespread, reversible chemical modification of
RNA molecules, implicated in many aspects of RNA metabolism. Little quantitative …
RNA molecules, implicated in many aspects of RNA metabolism. Little quantitative …
Genetic drivers of m6A methylation in human brain, lung, heart and muscle
The most prevalent post-transcriptional mRNA modification, N 6-methyladenosine (m6A),
plays diverse RNA-regulatory roles, but its genetic control in human tissues remains …
plays diverse RNA-regulatory roles, but its genetic control in human tissues remains …
N6-methyladenosine–encoded epitranscriptomics
Abstract N 6-methyladenosine (m 6 A) is the most abundant internal modification in
eukaryotic mRNA. Recent discoveries of the locations, functions and mechanisms of m 6 A …
eukaryotic mRNA. Recent discoveries of the locations, functions and mechanisms of m 6 A …
The biogenesis and precise control of RNA m6A methylation
N 6-Methyladenosine (m 6 A) is the most prevalent internal RNA modification in mRNA, and
has been found to be highly conserved and hard-coded in mammals and other eukaryotic …
has been found to be highly conserved and hard-coded in mammals and other eukaryotic …
Exon architecture controls mRNA m6A suppression and gene expression
N 6-methyladenosine (m6A) is the most abundant messenger RNA (mRNA) modification
and plays crucial roles in diverse physiological processes. Using a massively parallel assay …
and plays crucial roles in diverse physiological processes. Using a massively parallel assay …
N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis
RR Edupuganti, S Geiger, RGH Lindeboom… - Nature structural & …, 2017 - nature.com
RNA modifications are integral to the regulation of RNA metabolism. One abundant mRNA
modification is N 6-methyladenosine (m6A), which affects various aspects of RNA …
modification is N 6-methyladenosine (m6A), which affects various aspects of RNA …
m6A-TSHub: Unveiling the Context-Specific m6A Methylation and m6A-Affecting Mutations in 23 Human Tissues
As the most pervasive epigenetic marker present on mRNAs and long non-coding RNAs
(lncRNAs), N 6-methyladenosine (m6A) RNA methylation has been shown to participate in …
(lncRNAs), N 6-methyladenosine (m6A) RNA methylation has been shown to participate in …
m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome
Abstract N 6-Methyladenosine (m6A) is the most prevalent RNA modification on mRNAs and
lncRNAs. It plays a pivotal role during various biological processes and disease …
lncRNAs. It plays a pivotal role during various biological processes and disease …