A new method to determine dispersive surface energy site distributions by inverse gas chromatography

RR Smith, DR Williams, DJ Burnett, JYY Heng - Langmuir, 2014 - ACS Publications
A computational model to predict the relative energy site contributions of a heterogeneous
material from data collected by finite dilution–inverse gas chromatography (FD-IGC) is …

Computing the surface energy distributions of heterogeneous crystalline powders

AE Jefferson, DR Williams… - Journal of adhesion …, 2011 - Taylor & Francis
Inverse Gas Chromatography (IGC) provides a powerful tool for assessing the surface
energy of powders by using different chemicals as probes. Finite Dilution Inverse Gas …

Surface energy analysis as a tool to probe the surface energy characteristics of micronized materials—A comparison with inverse gas chromatography

JF Gamble, M Leane, D Olusanmi, M Tobyn… - International journal of …, 2012 - Elsevier
This study investigates the impact of micronization on the measured surface energy
characteristics of an active pharmaceutical ingredient (API), Ibipinabant, by inverse gas …

Surface heterogeneity: Information from inverse gas chromatography and application to model pharmaceutical substances

L Lapčík, M Otyepka, E Otyepková, B Lapčíková… - Current Opinion in …, 2016 - Elsevier
The general theory of electrokinetic phenomena strictly applies to ideal and rigid surfaces or
particles. However, many interfaces are non-ideal with respect to both the surface …

Investigating the applicability of inverse gas chromatography to binary powdered systems: An application of surface heterogeneity profiles to understanding …

JF Gamble, RN Davé, S Kiang, MM Leane… - International journal of …, 2013 - Elsevier
The aim of this study was to investigate the applicability of surface energy characterization
tools such as inverse gas chromatography for the analysis of binary systems. Drug …

Analysis of the surface energy of pharmaceutical powders by inverse gas chromatography

IM Grimsey, JC Feeley, P York - Journal of pharmaceutical sciences, 2002 - Elsevier
The behavior of pharmaceutical solids, during either processing or use, can be noticeably
affected by the surface energetics of the constituent particles. Several techniques exist to …

The importance of surface energetics of powders for drug delivery and the establishment of inverse gas chromatography

G Buckton, H Gill - Advanced drug delivery reviews, 2007 - Elsevier
Powders are complex systems with more than one value for surface energy. The presence of
different faces, defects, physical forms and impurities will alter the surface properties. There …

Critical assessment of inverse gas chromatography as means of assessing surface free energy and acid–base interaction of pharmaceutical powders

MJ Telko, AJ Hickey - Journal of pharmaceutical sciences, 2007 - Elsevier
Inverse gas chromatography (IGC) has been employed as a research tool for decades.
Despite this record of use and proven utility in a variety of applications, the technique is not …

Determination of the polar and total surface energy distributions of particulates by inverse gas chromatography

SC Das, I Larson, DAV Morton, PJ Stewart - Langmuir, 2011 - ACS Publications
This Letter reports a technique of measuring polar surface energy distributions of lactose
using inverse gas chromatography (IGC). The significance of this study is that the total …

The effective surface energy of heterogeneous solids measured by inverse gas chromatography at infinite dilution

C Sun, JC Berg - Journal of colloid and interface science, 2003 - Elsevier
Inverse gas chromatography (IGC) at infinite dilution has been widely used to access the
nonspecific surface free energy of solid materials. Since most practical surfaces are …