Chronic inflammation drives the development of atherosclerosis, and adaptive immunity is
deeply involved in this process. Initial studies attributed a pathogenic role to T cells in …

Chronic inflammation in response to lipoprotein accumulation in the arterial wall is central in
the development of atherosclerosis. Both innate and adaptive immunity are involved in this …

Atherosclerosis is an inflammatory and multifaceted disorder resulting from the accumulation
of lipid droplets and several types of immune cells, including macrophages, T and B …

Far from being merely a passive cholesterol accumulation within the arterial wall, the
development of atherosclerosis is currently known to imply both inflammation and immune …

Atherosclerosis involves the formation of inflammatory arterial lesions and is one of the most
common causes of death globally. It has been evident for more than 20 years that adaptive …

Although the pathogenic role of T cells in atherogenesis is well established, the function of
the various T-cell subsets is far from clear. Whereas activation of the T-helper type 1 (Th1) …

Atherosclerosis and related complications still represent the major cause of morbidity and
mortality in the western world. The mechanisms that govern the progression and …

Adaptive immune response plays an important role in atherogenesis. In atherosclerosis, the
proinflammatory immune response driven by Th1 is predominant but the anti-inflammatory …

Insights into the important contribution of inflammation and immune functions in the
development and progression of atherosclerosis have greatly improved our understanding …

Atherosclerosis is an inflammatory disease of the arterial wall where both innate and
adaptive T-cell-driven immunoinflammatory responses contribute to disease development …