The development of the mammalian kidney is a complex and in part unknown process which
requires interactions between pluripotential/stem cells, undifferentiated mesenchymal cells …

The embryonic kidney is an excellent model system in which to address many fundamental
issues in developmental biology. Inductive interactions are required for proliferation and …

Development of the metanephric kidney is strongly dependent on complex signaling
pathways and cell–cell communication between at least four major progenitor cell …

While kidney donations stagnate, the number of people in need of kidney transplants
continues to grow. Although transplanting culture-grown organs is years away, pursuing the …

Abstract Development of the kidney serves as a paradigm to understand the mechanisms
underlying the formation of an organ. The first sign of kidney development is the interaction …

Kidney development starts with the reciprocal induction of mesenchymal and ureteric bud
cells which leads to condensation, epithelialization, and nephron formation in the …

The conversion of intermediate mesoderm into renal tubular structures occurs throughout
embryonic development from the formation of the nephric duct through to the generation of …

Kidney Development, Disease, Repair and Regeneration focuses on the molecular and
cellular basis of kidney development, exploring the origins of kidney lineages, the …

The transporting epithelia of the kidney are derived from an embryonic rudiment containing
two distinct cell populations: ureteric bud epithelia and mesenchymal cells of the …

Most vertebrate organs, once formed, continue to perform the function for which they were
generated until the death of the organism. The kidney is a notable exception to this rule …