Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major public health issue. COVID-19 is considered an airway/multi-systemic disease, and demise has been …
Q Liu, Y Shi, J Cai, Y Duan, R Wang… - National science …, 2020 - academic.oup.com
Systematic autopsy and comprehensive pathological analyses of COVID-19 decedents should provide insights into the disease characteristics and facilitate the development of …
B Vijayakumar, K Boustani, PP Ogger, A Papadaki… - Immunity, 2022 - cell.com
Some patients hospitalized with acute COVID-19 suffer respiratory symptoms that persist for many months. We delineated the immune-proteomic landscape in the airways and …
M Wu, Y Chen, H Xia, C Wang… - Proceedings of the …, 2020 - National Acad Sciences
Coronavirus disease 2019 (COVID-19), the global pandemic caused by SARS-CoV-2, has resulted thus far in greater than 933,000 deaths worldwide; yet disease pathogenesis …
A Saris, TDY Reijnders, EJ Nossent, AR Schuurman… - Thorax, 2021 - thorax.bmj.com
Background Knowledge of the pathophysiology of COVID-19 is almost exclusively derived from studies that examined the immune response in blood. We here aimed to analyse the …
The clinical manifestation of coronavirus disease 2019 (COVID‐19) mainly targets the lung as a primary affected organ, which is also a critical site of immune cell activation by severe …
IS Cheon, C Li, YM Son, NP Goplen, Y Wu… - Science …, 2021 - science.org
Severe coronavirus disease 2019 (COVID-19) pneumonia survivors often exhibit long-term pulmonary sequelae, but the underlying mechanisms or associated local and systemic …
CD Russell, A Valanciute, NN Gachanja… - American journal of …, 2022 - atsjournals.org
Immunopathology occurs in the lung and spleen in fatal coronavirus disease (COVID-19), involving monocytes/macrophages and plasma cells. Antiinflammatory therapy reduces …