AL Portillo, JK Monteiro, EA Rojas, TM Ritchie… - Frontiers in …, 2023 - frontiersin.org
The ability to expand and activate natural Killer (NK) cells ex vivo has dramatically changed the landscape in the development of novel adoptive cell therapies for treating cancer over …
Natural killer (NK) cells are cytotoxic and cytokine-secreting cells that can mediate potent anti-tumour activity. Accumulating evidence indicates that NK cell functions are severely …
S Liu, P Dhar, JD Wu - Journal of Clinical Medicine, 2019 - mdpi.com
Natural killer (NK) cells are critical immune components in controlling tumor growth and dissemination. Given their innate capacity to eliminate tumor cells without prior sensitization …
C Di Vito, J Mikulak, E Zaghi, S Pesce… - Seminars in …, 2019 - Elsevier
Natural Killer (NK) cells are innate lymphocytes able to mediate immune-surveillance and clearance of viral infected and tumor-transformed cells. Growing experimental and clinical …
Natural killer (NK) cells belong to the innate immune system and contribute to protecting the host through killing of infected, foreign, stressed or transformed cells. Additionally, via …
A Ben-Shmuel, G Biber, M Barda-Saad - Frontiers in immunology, 2020 - frontiersin.org
The emergence of immunotherapy for cancer treatment bears considerable clinical promise. Nevertheless, many patients remain unresponsive, acquire resistance, or suffer dose …
Natural killer cells are powerful effectors of innate immunity that constitute a first line of defense against cancer. NK cells express an array of germline-encoded receptors which …
Y Zhou, L Cheng, L Liu, X Li - Molecular Cancer, 2023 - Springer
Immune escape is a hallmark of cancer. The dynamic and heterogeneous tumour microenvironment (TME) causes insufficient infiltration and poor efficacy of natural killer (NK) …
Z Hu, X Xu, H Wei - Frontiers in Immunology, 2021 - frontiersin.org
NK cells are considered an important component of innate immunity, which is the first line of defensing against tumors and viral infections in the absence of prior sensitization. NK cells …