[PDF][PDF] Favorable anakinra responses in severe Covid-19 patients with secondary hemophagocytic lymphohistiocytosis

G Dimopoulos, Q de Mast, N Markou… - Cell host & …, 2020 - cell.com
Dysregulation of inflammation is hypothesized to play a crucial role in the severe
complications of COVID-19, with the IL-1/IL-6 pathway being central. Here, we report on the …

Preliminary predictive criteria for COVID-19 cytokine storm

R Caricchio, M Gallucci, C Dass, X Zhang… - Annals of the …, 2021 - ard.bmj.com
Objectives To develop predictive criteria for COVID-19-associated cytokine storm (CS), a
severe hyperimmune response that results in organ damage in some patients infected with …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
COVID-19 has claimed millions of lives during the last 3 years since initial cases were
reported in Wuhan, China, in 2019. Patients with COVID-19 suffer from severe pneumonia …

Macrophage activation syndrome and COVID-19

R Otsuka, K Seino - Inflammation and regeneration, 2020 - Springer
An emerging, rapidly spreading coronavirus SARS-CoV-2 is causing a devastating
pandemic. As we have not developed curative medicine and effective vaccine, the end of …

[HTML][HTML] Cytokine storm in COVID-19:“when you come out of the storm, you won't be the same person who walked in”

V Castelli, A Cimini, C Ferri - Frontiers in immunology, 2020 - frontiersin.org
In December 2019, a novel coronavirus, COVID-19, was discovered to be the causal agent
of a severe respiratory infection named SARS-CoV-2, and it has since been recognized …

Hematological manifestations of COVID-19

A Mina, K Van Besien, LC Platanias - Leukemia & lymphoma, 2020 - Taylor & Francis
The emergence of the Coronavirus Disease− 19 (COVID-19) pandemic, has had a
tremendous global impact, resulting in substantial morbidity and mortality worldwide and …

[HTML][HTML] Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome

LB Afrin, LB Weinstock, GJ Molderings - International journal of infectious …, 2020 - Elsevier
Abstract Objectives One-fifth of Covid-19 patients suffer a severe course of Covid-19
infection; however, the specific causes remain unclear. Mast cells (MCs) are activated by …

Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and …

J Wang, M Jiang, X Chen… - Journal of Leucocyte …, 2020 - academic.oup.com
Clinical evidence indicates that the fatal outcome observed with severe acute respiratory
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …

Role for anti-cytokine therapies in severe coronavirus disease 2019

LF Buckley, GF Wohlford, C Ting… - Critical care …, 2020 - journals.lww.com
Objectives: The causative agent for coronavirus disease 2019, severe acute respiratory
syndrome coronavirus 2, appears exceptional in its virulence and immunopathology. In …

Cytokine release syndrome in severe COVID-19

JB Moore, CH June - Science, 2020 - science.org
In December 2019, a new strain of coronavirus, severe acute respiratory syndrome–
coronavirus 2 (SARS-CoV-2), was recognized to have emerged in Wuhan, China. Along …