Human genetic disorders resulting in systemic selenoprotein deficiency
E Schoenmakers, K Chatterjee - International journal of molecular …, 2021 - mdpi.com
Selenium, a trace element fundamental to human health, is incorporated as the amino acid
selenocysteine (Sec) into more than 25 proteins, referred to as selenoproteins. Human …
selenocysteine (Sec) into more than 25 proteins, referred to as selenoproteins. Human …
Mice lacking selenoprotein P and selenocysteine lyase exhibit severe neurological dysfunction, neurodegeneration, and audiogenic seizures
Selenoproteins are a unique family of proteins, characterized by the co-translational
incorporation of selenium as selenocysteine, which play key roles in antioxidant defense …
incorporation of selenium as selenocysteine, which play key roles in antioxidant defense …
Cell-type specific analysis of selenium-related genes in brain
Selenoproteins are a unique class of proteins that play key roles in redox signaling in the
brain. This unique organ is comprised of a wide variety of cell types that includes excitatory …
brain. This unique organ is comprised of a wide variety of cell types that includes excitatory …
Selenium in biology: facts and medical perspectives
J Köhrle, R Brigelius-Flohé, A Böck, R Gärtner… - 2000 - degruyter.com
Several decades after the discovery of selenium as an essential trace element in vertebrates
approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the …
approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the …
Selenium biochemistry and its role for human health
M Roman, P Jitaru, C Barbante - Metallomics, 2014 - academic.oup.com
Despite its very low level in humans, selenium plays an important and unique role among
the (semi) metal trace essential elements because it is the only one for which incorporation …
the (semi) metal trace essential elements because it is the only one for which incorporation …
Selenium and selenoproteins in mammals: extraordinary, essential, enigmatic
Selenium (Se), once known only for its potential toxicity, is now well established as an
essential trace element for mammals. Insufficient Se intake predisposes to and manifests in …
essential trace element for mammals. Insufficient Se intake predisposes to and manifests in …
Roles of selenoproteins in brain function and the potential mechanism of selenium in Alzheimer's disease
ZH Zhang, GL Song - Frontiers in Neuroscience, 2021 - frontiersin.org
Selenium (Se) and its compounds have been reported to have great potential in the
prevention and treatment of Alzheimer's disease (AD). However, little is known about the …
prevention and treatment of Alzheimer's disease (AD). However, little is known about the …
The brain selenoproteome: priorities in the hierarchy and different levels of selenium homeostasis in the brain of selenium‐deficient rats
M Kühbacher, J Bartel, B Hoppe, D Alber… - Journal of …, 2009 - Wiley Online Library
The application of radionuclides for the localization of essential trace elements in vivo and
the characterization of their binding proteins is a story of intermittently made improvements …
the characterization of their binding proteins is a story of intermittently made improvements …
Selenium and the brain: a review
PD Whanger - Nutritional neuroscience, 2001 - Taylor & Francis
Similar to other tissues selenium from selenomethionine is deposited in the brain at higher
concentrations than selenium in other forms. Vitamin E has a greater effect than selenium in …
concentrations than selenium in other forms. Vitamin E has a greater effect than selenium in …
From selenium to selenoproteins: synthesis, identity, and their role in human health
The requirement of the trace element selenium for life and its beneficial role in human health
has been known for several decades. This is attributed to low molecular weight selenium …
has been known for several decades. This is attributed to low molecular weight selenium …