Methylation recognition protein YTH N6-methyladenosine RNA binding protein 1 (YTHDF1) regulates the proliferation, migration and invasion of osteosarcoma by …

K Wei, Y Gao, B Wang, YX Qu - Bioengineered, 2022 - Taylor & Francis
ABSTRACT N6-methyladenosine (m6A) is one of the most significant modifications in
human mRNAs. Emerging evidence indicates that m6A participates in the initiation and …

METTL3 upregulates COPS5 expression in osteosarcoma in an m6A-related manner to promote osteosarcoma progression

C Zhang, J Wan, Q Liu, F Long, Z Wen, Y Liu - Experimental Cell Research, 2022 - Elsevier
Abstract N6-methyladenosine (m 6 A) is the most abundant and well-studied internal
modification of messenger RNAs (mRNAs). Although m 6 A mRNA modification has been …

[HTML][HTML] YTHDF1 regulates tumorigenicity and cancer stem cell-like activity in human colorectal carcinoma

Y Bai, C Yang, R Wu, L Huang, S Song, W Li… - Frontiers in …, 2019 - frontiersin.org
YTH N6-methyladenosine (m6A) RNA binding protein 1 (YTHDF1) is a core factor in RNA
methylation modification. Recent studies have shown that m6A is closely related to multiple …

The m6A methyltransferase METTL3 promotes osteosarcoma progression by regulating the m6A level of LEF1

W Miao, J Chen, L Jia, J Ma, D Song - Biochemical and biophysical …, 2019 - Elsevier
Osteosarcoma (OS) is the most common and aggressive malignant bone sarcoma, which
occurs in rapidly growing bones in children and adolescents. However, the underlying …

[HTML][HTML] YTHDF2 Regulates Cell Growth and Cycle by Facilitating KDM1A mRNA Stability

X Li, KJ Zhang, Y Hu, N Luo - The American Journal of Pathology, 2023 - Elsevier
Breast cancer is the leading cause of cancer death in women. The physiological functions of
N6-methyladenosine methylation in cancer have been the focus of studies in recent years …

Knockdown of YTH N6-methyladenosine RNA binding protein 2 (YTHDF2) inhibits cell proliferation and promotes apoptosis in cervical cancer cells

Z Li, Q Luo, H Wang, Y Liu, X Feng… - Xi bao yu fen zi mian yi xue …, 2020 - europepmc.org
Objective To investigate the effect of YTH N6-methyladenosine RNA binding protein 2
(YTHDF2) knockdown on proliferation, cell cycle and apoptosis of cervical cancer cells …

METTL3 mediated MALAT1 m6A modification promotes proliferation and metastasis in osteosarcoma cells

Y Zhang, Y Xu, G Qiu, Y Luo, Y Bao, J Lu, T Wang… - Molecular …, 2023 - Springer
Background As one of the most ubiquitous types of posttranscriptional modification, N6-
methyladenosine (m6A) is extensively implicated in almost all types of cancers, including …

Knockdown of YTH N6-methyladenosine RNA binding protein 2 (YTHDF2) inhibits proliferation and promotes apoptosis in MGC-803 gastric cancer cells

J Zhang, J Pi, Y Liu, J Yu, T Feng - Xi bao yu fen zi mian yi xue za …, 2017 - europepmc.org
Objective To investigate the effect of knockdown of YTH N6-methyladenosine RNA binding
protein 2 (YTHDF2) on cell proliferation, cell cycle and apoptosis of MGC-803 human gastric …

[HTML][HTML] Potential role of m6A RNA methylation regulators in osteosarcoma and its clinical prognostic value

H Liu, G Qin, Y Ji, X Wang, H Bao, X Guan… - Journal of Orthopaedic …, 2021 - Springer
Background Osteosarcoma is a disease with high mortality in children and adolescents, and
metastasis is one of the important clinical features of osteosarcoma. N 6-Methyladenosine …

RNA m6A Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway

J Cai, F Yang, H Zhan, J Situ, W Li, Y Mao… - OncoTargets and …, 2019 - Taylor & Francis
Purpose N6-methyladenosine (m6A) is the most abundant internal modification on
eukaryotic mRNA and gained increasing attention recently. More and more evidence …