Interleukin (IL)-6 has been studied since its discovery for its role in health and diseases. It is
one of the most important pro-inflammatory cytokines. IL-6 was reported as an exacerbating …

The detrimental impact of obesity on human health is increasingly evident with the rise in
obesity-related diseases. Skeletal muscle, the crucial organ responsible for energy balance …

Hepatic lipid dysregulation can lead to spectrum of metabolic disease conditions including
metabolic syndrome (MS), fatty liver and diabetes. Liver lipids are regulated by a complex …

The circulating level of the inflammatory cytokine interleukin (IL)-6 is elevated in various
insulin-resistant states including type 2 diabetes, obesity, cancer, and HIV-associated …

Abstract Interleukin-15 (IL-15) is essential for the homeostasis of lymphoid cells particularly
memory CD8+ T cells and NK cells. These cells are abundant in the liver, and are implicated …

Objective: Abundant evidence has demonstrated that long-term cytokine-mediated
inflammation is a risk factor for obesity and type 2 diabetes mellitus (T2DM). Our previous …

Background Various cytokines and other compounds are produced in human adipose tissue
and might have functions in the adipose tissue. They might be involved in complications …

Long-term cytokine-mediated inflammation is a risk factor for obesity and type 2 diabetes
mellitus (T2DM). Our previous studies reveal significant associations between promoter …

The liver, as a central metabolic organ, is systemically linked to metabolic–inflammatory
diseases. In the pathogenesis of the metabolic syndrome, inflammatory and metabolic …

Interleukin (IL)‐6 is a cytokine with pleiotropic functions in different tissues and organs.
Skeletal muscle produces and releases significant levels of IL‐6 after prolonged exercise …