The early window of human embryogenesis is largely a black box for developmental
biologists. Here we probed the cellular diversity of 4-to 6-week human embryos when …

The early window of human embryogenesis is largely a black box for developmental
biologists. Here we probed the cellular diversity of 4–6 week human embryos when …

Genome-wide expression analysis of embryonic development provides information that is
useful in a variety of contexts. Here, we report transcriptome profiles of human early embryos …

Mammalian embryos exhibit sophisticated cellular patterning that is intricately orchestrated
at both molecular and cellular level. It has recently become apparent that cells within the …

Progress in understanding early human development has been impeded by the scarcity of
reference datasets from natural embryos, particularly those with spatial information during …

Despite its clinical and fundamental importance, our understanding of early human
development remains limited. Stem cell-derived, embryo-like structures (or embryoids) …

Background Organogenesis is crucial for proper organ formation during mammalian
embryonic development. However, the similarities and shared features between different …

Early organogenesis represents a key step in animal development, during which pluripotent
cells diversify to initiate organ formation. Here, we sampled 300,000 single-cell …

Biomedical research relies heavily on the use of model organisms to gain insight into human
health and development. Traditionally, the mouse has been the favored vertebrate model …

Transcriptional and epigenetic profiling of single-cells has advanced our knowledge of the
molecular bases of gastrulation and early organogenesis. However, current approaches rely …