The NF-κB/Rel signaling system is a paradigm for gene activation in response to
inflammatory and menacing stimuli. Given the growing body of evidence showing an …

Nuclear factor (NF)-κB governs the expression of numerous genes that are important for
various cellular responses. Its activation is induced by a wide variety of stimuli including …

The nuclear factor-κB (NF-κB)/REL family of transcription factors has a central role in
coordinating the expression of a wide variety of genes that control immune responses. There …

In the 20 years since its discovery, research into the NF-κB (nuclear factor-κB) family of
transcription factors has revealed an amazing diversity of functions. NF-κB proteins are …

Simple Summary Since its first description 35 years ago, the transcription factor NF-κB
(nuclear factor κ-light-chain-enhancer of activated B cells) has been shown to be a key …

The IκB kinase/NF-κB signaling pathway has been implicated in the pathogenesis of several
inflammatory diseases. Increased activation of NF-κB is often detected in both immune and …

The NF-κB pathway is a critical regulator of immune responses and is often dysregulated in
cancer. Two NF-κB pathways have been described to mediate these responses, the …

Nuclear factor kappa B (NF-κB) is a family of inducible transcription factors found virtually
ubiquitously in all cells. Since its discovery by Sen and Baltimore in 1986, much has been …

Activation of NF-κB has been linked to various cellular processes in cancer, including
inflammation, transformation, proliferation, angiogenesis, invasion, metastasis …

Recent studies have clearly linked nuclear factor-kappaB (NF-κB), a transcription factor that
plays a central role in regulating immune and inflammatory responses, to tumor …