NFκB was identified 20 years ago (Sen, R., & Baltimore, D.(1986) Cell, 46, 705–716) as a
nuclear factor that binds the κ light chain enhancer in B-cells (and hence, the name NFκB) …

Nuclear factor κB (NF‐κB) belongs to a family of heterodimeric transcription factors that play
a key role in inflammatory and stress responses as well as in tumor cell resistance to …

Fourteen years have passed since nuclear factor-κB (NF-κB) was first shown to serve as a
molecular lynchpin that links persistent infections and chronic inflammation to increased …

Nuclear factor‐κΒ (NF‐κB) binds specifically to NF‐κB‐binding sites (κB sites, 5′‐
GGGRNNYYCC‐3′; R, purine; Y, pyrimidine; N, any nucleotide) present in enhancer …

Nuclear transcription factor κB (NF-κB) was first discovered in 1986 in the nucleus of the B
cell as an enhancer in the κ immunoglobulin chain. However, this factor has identified in the …

The nuclear factor-κB (NF-κB) family of transcription factors is activated by canonical and
non-canonical signalling pathways, which differ in both signalling components and …

The nuclear factor-kappaB (NF-κB) family of transcription factors are involved in multiple
cellular processes, including cytokine gene expression, cellular adhesion, cell cycle …

The inflammatory response is of major importance in host defence, but is involved in all
acute and chronic diseases. Multiple inflammatory cells and molecules are involved. Among …

Conclusions Overall these studies clearly demonstrate that NF-κB plays a critical role in
tumorigenesis. Similarity, suppression of NF-κB has the ability to inhibit various steps in the …

In the 25 years since its discovery, the nuclear factor-κB (NF-κB) family of transcription
factors has been the subject of intensive research in virtually all areas of biomedical science …