HDL biogenesis and functions: role of HDL quality and quantity in atherosclerosis

EM Tsompanidi, MS Brinkmeier, EH Fotiadou… - Atherosclerosis, 2010 - Elsevier
Coronary heart disease (CHD) is a leading cause of death in western societies. In the last
few decades, a number of epidemiological studies have shown that a disproportion between …

Metabolism of HDL and its regulation

D Kardassis, I Mosialou, M Kanaki… - Current medicinal …, 2014 - ingentaconnect.com
Epidemiological studies have shown that low plasma levels of High Density Lipoprotein
Cholesterol (HDL-C) are associated with an increased risk for myocardial infarction. These …

Is a high HDL-cholesterol level always beneficial?

B Franczyk, J Rysz, J Ławiński, M Rysz-Górzyńska… - Biomedicines, 2021 - mdpi.com
The specific interest concerning HDL cholesterol (HDL-C) is related to its ability to uptake
and return surplus cholesterol from peripheral tissues back to the liver and, therefore, to its …

HDL and atherosclerosis: Insights from inherited HDL disorders

L Calabresi, M Gomaraschi, S Simonelli… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Plasma high density lipoproteins (HDL) comprise a highly heterogeneous family of
lipoprotein particles, differing in density, size, surface charge, and lipid and protein …

Health benefits of high-density lipoproteins in preventing cardiovascular diseases

H Berrougui, CN Momo, A Khalil - Journal of clinical lipidology, 2012 - Elsevier
Plasma levels of high-density lipoprotein (HDL) are strongly and inversely correlated with
atherosclerotic cardiovascular diseases. However, it is becoming clear that a functional HDL …

The metabolism and anti-atherogenic properties of HDL

KA Rye, CA Bursill, G Lambert, F Tabet… - Journal of lipid research, 2009 - ASBMB
Population studies have shown that plasma HDL levels correlate inversely with
cardiovascular disease risk. In recent years there has been intense interest in developing …

Update on strategies to increase HDL quantity and function

D Duffy, DJ Rader - Nature Reviews Cardiology, 2009 - nature.com
Low levels of HDL cholesterol are a significant predictor of atherosclerotic cardiovascular
events. HDL is believed to protect against atherosclerosis by promoting reverse cholesterol …

The HDL hypothesis: does high-density lipoprotein protect from atherosclerosis?

M Vergeer, AG Holleboom, JJP Kastelein… - Journal of lipid …, 2010 - ASBMB
There is unequivocal evidence of an inverse association between plasma high-density
lipoprotein (HDL) cholesterol concentrations and the risk of cardiovascular disease, a …

HDL in atherosclerotic cardiovascular disease: in search of a role

M Casula, O Colpani, S Xie, AL Catapano, A Baragetti - Cells, 2021 - mdpi.com
For a long time, high-density lipoprotein cholesterol (HDL-C) has been regarded as a
cardiovascular disease (CVD) protective factor. Recently, several epidemiological studies …

[PDF][PDF] Dysfunctional HDL: from structure-function-relationships to biomarkers

M Riwanto, L Rohrer, A von Eckardstein… - High Density …, 2015 - library.oapen.org
Reduced plasma levels of HDL-C are associated with an increased risk of CAD and
myocardial infarction, as shown in various prospective population studies. However, recent …