[HTML][HTML] Longitudinal cytokine profile in patients with mild to critical COVID-19

L Ling, Z Chen, G Lui, CK Wong, WT Wong… - Frontiers in …, 2021 - frontiersin.org
The cytokine release syndrome has been proposed as the driver of inflammation in
coronavirus disease 2019 (COVID-19). However, studies on longitudinal cytokine profiles in …

[HTML][HTML] A deep look into COVID-19 severity through dynamic changes in blood cytokine levels

DA Kleymenov, EN Bykonia, LI Popova… - Frontiers in …, 2021 - frontiersin.org
An excessive inflammatory response to SARS-CoV-2 is thought to be a major cause of
disease severity and mortality in patients with COVID-19. Longitudinal analysis of cytokine …

Cytokines and their relationship with the severity and prognosis of coronavirus disease 2019 (COVID-19): a retrospective cohort study

QQ Liu, A Cheng, Y Wang, H Li, L Hu, X Zhao… - BMJ open, 2020 - bmjopen.bmj.com
Objective To delineate the characteristics and clinical significance of plasma inflammatory
cytokines altered in COVID-19. Design Retrospective, single-centre cohort study. Setting …

Cytokine release syndrome in COVID-19: Innate immune, vascular, and platelet pathogenic factors differ in severity of disease and sex

AC Petrey, F Qeadan, EA Middleton… - Journal of Leucocyte …, 2021 - academic.oup.com
COVID-19 rapidly emerged as a crippling public health crisis in the last few months, which
has presented a series health risk. Understanding of the immune response and biomarker …

Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors

H Han, Q Ma, C Li, R Liu, L Zhao, W Wang… - Emerging microbes & …, 2020 - Taylor & Francis
Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly
spread across many other countries. While the majority of patients were considered mild …

[HTML][HTML] Cytokine signature associated with disease severity in COVID-19

J Guo, S Wang, H Xia, D Shi, Y Chen, S Zheng… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) broke out and then became a global epidemic at the
end of 2019. With the increasing number of deaths, early identification of disease severity …

An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis

Y Liu, D Chen, J Hou, H Li, D Cao, M Guo, Y Ling… - Cytokine, 2021 - Elsevier
The hyper-inflammatory response is thought to be a major cause of acute respiratory
distress syndrome (ARDS) in patients with COVID-19. Although multiple cytokines are …

Distinct cytokine profiles associated with COVID-19 severity and mortality

K Dorgham, P Quentric, M Gökkaya, S Marot… - Journal of Allergy and …, 2021 - Elsevier
Background Markedly elevated levels of proinflammatory cytokines and defective type-I
interferon responses were reported in patients with coronavirus disease 2019 (COVID-19) …

Dysregulated innate and adaptive immune responses discriminate disease severity in COVID-19

NAF Janssen, I Grondman… - The Journal of …, 2021 - academic.oup.com
The clinical spectrum of COVID-19 varies and the differences in host response
characterizing this variation have not been fully elucidated. COVID-19 disease severity …

[HTML][HTML] The anti-inflammatory cytokine response characterized by elevated interleukin-10 is a stronger predictor of severe disease and poor outcomes than the pro …

BM Henry, SW Benoit, J Vikse, BA Berger… - Clinical Chemistry and …, 2021 - degruyter.com
Objectives Severe coronavirus disease 2019 (COVID-19) is associated with a dysregulated
immune state. While research has focused on the hyperinflammation, little research has …