A Blood-Based Lipid Profile Associated With Hippocampal Volume and Brain Resting-State Activation Within Obese Adults from the UK Biobank
Objectives: Obesity and dyslipidemia may be associated with hippocampal alterations and
may increase the risk of neurodegeneration. This study studied hippocampal anatomical …
may increase the risk of neurodegeneration. This study studied hippocampal anatomical …
Longitudinal changes in fat mass and the hippocampus
Objective This study aimed to investigate cross‐sectional and longitudinal associations
between fat mass (ie, body mass index [BMI], waist circumference [WC], and waist to hip …
between fat mass (ie, body mass index [BMI], waist circumference [WC], and waist to hip …
[HTML][HTML] Central obesity is selectively associated with cerebral gray matter atrophy in 15,634 subjects in the UK Biobank
Background Obesity is a risk factor for both cardiovascular disease and dementia, but the
mechanisms underlying this association are not fully understood. We examined associations …
mechanisms underlying this association are not fully understood. We examined associations …
Lower functional hippocampal connectivity in healthy adults is jointly associated with higher levels of leptin and insulin resistance
Background Metabolic dysregulation is currently considered a major risk factor for
hippocampal pathology. The aim of the present study was to characterize the influence of …
hippocampal pathology. The aim of the present study was to characterize the influence of …
Hippocampal volume reduction is associated with direct measure of insulin resistance in adults
Hippocampal integrity is highly susceptible to metabolic dysfunction, yet its mechanisms are
not well defined. We studied 126 healthy individuals aged 23–61 years. Insulin resistance …
not well defined. We studied 126 healthy individuals aged 23–61 years. Insulin resistance …
Obesity impairs cognitive function via metabolic syndrome and cerebrovascular disease: an SEM analysis in 15,000 adults from the UK Biobank
Chronic obesity is associated with several complications, including cognitive impairment
and dementia. However, we have piecemeal knowledge of the mechanisms linking obesity …
and dementia. However, we have piecemeal knowledge of the mechanisms linking obesity …
Being overweight is associated with hippocampal atrophy: the PATH Through Life Study
N Cherbuin, K Sargent-Cox, M Fraser… - International journal of …, 2015 - nature.com
Background: The prevalence of obesity has increased dramatically in the past two decades,
with major implications for individual well-being, population health and the economy. Of …
with major implications for individual well-being, population health and the economy. Of …
[HTML][HTML] Effects of Body Mass Index on Brain Structures in the Elderly: Longitudinal Analyses
H Takeuchi, R Kawashima - Frontiers in Endocrinology, 2022 - frontiersin.org
The relationship between obesity and neurocognitive consequences is complex. Here we
investigated associations between body mass index (BMI) and subsequent changes in brain …
investigated associations between body mass index (BMI) and subsequent changes in brain …
Associations between body weight, hippocampal volume, and tissue signal intensity in 12‐to 18‐year‐olds
Z Mestre, A Bischoff-Grethe, CE Wierenga, T Jernigan… - …, 2020 - Wiley Online Library
Objective The hippocampus is a key structure in feeding behaviors and weight regulation.
Obesity may lead to disruptions in hippocampal structure. In animals, obesity‐related factors …
Obesity may lead to disruptions in hippocampal structure. In animals, obesity‐related factors …
[HTML][HTML] Metabolism-related brain morphology accelerates aging and predicts neurodegenerative diseases and stroke: a UK Biobank study
Abstracts Metabolic syndrome (MetS) is characterized by a constellation of metabolic risk
factors, including obesity, hypertriglyceridemia, low high-density lipoprotein (HDL) levels …
factors, including obesity, hypertriglyceridemia, low high-density lipoprotein (HDL) levels …