Compassionate remdesivir treatment of severe Covid-19 pneumonia in intensive care unit (ICU) and Non-ICU patients: Clinical outcome and differences in post …

S Antinori, MV Cossu, AL Ridolfo, R Rech… - Pharmacological …, 2020 - Elsevier
SARS-CoV-2 is causing an increasing number of deaths worldwide because no effective
treatment is currently available. Remdesivir has shown in vitro activity against coronaviruses …

Successful treatment of persistent SARS-CoV-2 infection in a B-cell depleted patient with activated cytotoxic T and NK cells: a case report

J Jassem, NM Marek-Trzonkowska, T Smiatacz… - International journal of …, 2021 - mdpi.com
We report a lymphoma patient with profound B-cell deficiency after chemotherapy combined
with anti-CD20 antibody successfully treated with remdesivir and convalescent plasma for …

[HTML][HTML] Effect of antiviral and immunomodulatory treatment on a cytokine profile in patients with COVID-19

D Martonik, A Parfieniuk-Kowerda, A Starosz… - Frontiers in …, 2023 - frontiersin.org
Background The severity of COVID-19 is associated with an elevated level of a variety of
inflammatory mediators. Increasing evidence suggests that the Th17 response contributes to …

Remdesivir for the treatment of Covid-19

JH Beigel, KM Tomashek, LE Dodd… - … England Journal of …, 2020 - Mass Medical Soc
Background Although several therapeutic agents have been evaluated for the treatment of
coronavirus disease 2019 (Covid-19), no antiviral agents have yet been shown to be …

Impact of remdesivir on the treatment of COVID-19 during the first wave in Spain

A Soriano, R Montejano, J Sanz-Moreno… - Advances in …, 2021 - Springer
Introduction Spain was one of the most affected countries during the first wave of COVID-19,
having the highest mortality rate in Europe. The aim of this retrospective study is to estimate …

Efficacy and safety of remdesivir over two waves of the SARS-CoV-2 pandemic

M Poliseno, C Gallo, DC Cibelli, GA Minafra… - Antibiotics, 2021 - mdpi.com
The aim of this study is to describe the features, the outcomes, and the clinical issues related
to Remdesivir administration of a cohort of 220 patients (pts) with COVID-19 hospitalized …

Clinical use of remdesivir in COVID-19 treatment: A retrospective cohort study

HT Pham, TA Mai-Phan, AK Vu, TH Truong, MH Tran - BMJ open, 2023 - bmjopen.bmj.com
Objectives This study investigated remdesivir's clinical use to provide direct evidence of
effectiveness for a low-middle income Asian setting. Design A one-to-one propensity score …

Pharmacokinetics of remdesivir and GS-441524 in two critically ill patients who recovered from COVID-19

M Tempestilli, P Caputi, V Avataneo… - Journal of …, 2020 - academic.oup.com
Background Remdesivir is a prodrug of the nucleoside analogue GS-441524 and is under
evaluation for treatment of SARS-CoV-2-infected patients. Objectives To evaluate the …

Remdesivir for the treatment of COVID-19

DCT Team - New England Journal of Medicine, 2020 - snucm.elsevierpure.com
BACKGROUND Although several therapeutic agents have been evaluated for the treatment
of coronavirus disease 2019 (Covid-19), no antiviral agents have yet been shown to be …

[HTML][HTML] Adverse events following remdesivir administration in moderately ill COVID-19 patients-A retrospective analysis

R Gandham, M Eerike, GM Raj, D Bisoi… - Journal of Family …, 2022 - journals.lww.com
Results: Out of the 160 COVID-19 patients, 32 were moderately ill (males: 29, females: 03)
and were treated with remdesivir along with steroids and low molecular weight heparin …