Effects of sex and the common ADRB1 389 genetic polymorphism on the hemodynamic response to dobutamine
D Yogev, M Basheer, S Blotnick, Y Caraco… - Pharmacogenetics …, 2015 - journals.lww.com
Results Resting heart rate (HR) response to 6 mcg/kg/min dobutamine (ΔHR) was 4.7-fold
larger in Arg389Arg than in Gly389Gly [(mean±SD) 12.95±6.99, 2.75±1.65 bpm …
larger in Arg389Arg than in Gly389Gly [(mean±SD) 12.95±6.99, 2.75±1.65 bpm …
Effect of the ADRB1 1165C>G and 145A>G polymorphisms on hemodynamic response during dobutamine stress echocardiography
A Banaś, E Płońska, M Kurzawski, W Gornik… - European journal of …, 2011 - Springer
Purpose The aim of this study was to determine an association between the ADRB1 1165C>
G and 145A> G polymorphisms and hemodynamic response [heart rate (HR), systolic (SBP) …
G and 145A> G polymorphisms and hemodynamic response [heart rate (HR), systolic (SBP) …
β-Adrenergic receptor gene polymorphisms and hemodynamic response to dobutamine during dobutamine stress echocardiography
CL Aquilante, HN Yarandi, LH Cavallari… - The …, 2008 - nature.com
Our objective was to determine if β 1-adrenergic receptor (β 1-AR) and β 2-AR gene
polymorphisms influence heart rate (HR), systolic blood pressure (SBP) and diastolic blood …
polymorphisms influence heart rate (HR), systolic blood pressure (SBP) and diastolic blood …
Functional effects of β1-adrenoceptor polymorphisms on the hemodynamic response to dobutamine with and without β-blocker administration
M Kindermann, U Seeland, P Ruhnke, M Böhm… - Clinical Research in …, 2011 - Springer
Background The relevance of the Arg389Gly-and Ser49Gly-β 1-adrenoceptor (AR)
polymorphisms for cardiovascular function and pharmacotherapy is controversial. Methods …
polymorphisms for cardiovascular function and pharmacotherapy is controversial. Methods …
The common Arg389gly ADRB1 polymorphism affects heart rate response to the ultra-short-acting β1 adrenergic receptor antagonist esmolol in healthy individuals
The β1-adrenergic receptor (β1AR) Arg389Gly polymorphism affects responses to orally
administered β1AR antagonists (β-blockers) in vivo. However, the effect of this …
administered β1AR antagonists (β-blockers) in vivo. However, the effect of this …
G16R single nucleotide polymorphism but not haplotypes of the β2-adrenergic receptor gene alters cardiac output in humans
KZ Rokamp, JM Staalsoe, M Gartmann… - Clinical …, 2013 - portlandpress.com
Variation in genes encoding the β2-adrenergic receptor (ADRB2) and angiotensin-
converting enzyme (ACE) may influence Q ̇ (cardiac output). The 46G> A (G16R) SNP …
converting enzyme (ACE) may influence Q ̇ (cardiac output). The 46G> A (G16R) SNP …
Effects of beta1-adrenoceptor genetic polymorphisms on resting hemodynamics in patients undergoing diagnostic testing for ischemia
LM Humma, BJ Puckett, HE Richardson… - American Journal of …, 2001 - ajconline.org
10q24. The codon 49 polymorphism is located in the receptor's extracellular aminoterminus
domain, and the codon 389 polymorphism is located in the proximal region of the …
domain, and the codon 389 polymorphism is located in the proximal region of the …
Arginine 16 glycine β2-adrenoceptor polymorphism and cardiovascular structure and function in patients with heart failure
R Wolk, EM Snyder, VK Somers, ST Turner… - Journal of the American …, 2007 - Elsevier
The β2/β1 adrenoceptor ratio increases in congestive heart failure (CHF), making the heart
relatively more dependent on inotropic, lusitropic, and chronotropic stimulation by the β2 …
relatively more dependent on inotropic, lusitropic, and chronotropic stimulation by the β2 …
Genotype related differences in beta2 adrenergic receptor density and cardiac function.
EM Snyder, ML Hulsebus, ST Turner… - Medicine and science …, 2006 - europepmc.org
Methods We measured ADRB2 density on isolated lymphocytes in 30 healthy subjects (15
homozygous for Arg, Arg16, and 15 homozygous for Gly, Gly16) matched for age …
homozygous for Arg, Arg16, and 15 homozygous for Gly, Gly16) matched for age …
[HTML][HTML] Influence of Beta-1 adrenergic receptor genotype on cardiovascular response to exercise in healthy subjects
EF Kelley, EM Snyder, BD Johnson - Cardiology research, 2018 - ncbi.nlm.nih.gov
Background The beta-1 adrenergic receptor (ADRB1) has been shown to play a functional
role in cardiomyocyte function and accounts for up to 80% of the cardiac tissue adrenergic …
role in cardiomyocyte function and accounts for up to 80% of the cardiac tissue adrenergic …