Metabolomics profiles associated with diabetic retinopathy in type 2 diabetes patients

JH Yun, JM Kim, HJ Jeon, T Oh, HJ Choi, BJ Kim - PLoS One, 2020 - journals.plos.org
Diabetic retinopathy (DR) is a common complication of diabetes, and it is the consequence
of microvascular retinal changes due to high glucose levels over a long time. Metabolomics …

Multiplatform metabolomics reveals novel serum metabolite biomarkers in diabetic retinopathy subjects

Q Xuan, Y Ouyang, Y Wang, L Wu, H Li… - Advanced …, 2020 - Wiley Online Library
Diabetic retinopathy (DR) is the main cause of vision loss or blindness in working age adults
worldwide. The lack of effective diagnostic biomarkers for DR leads to unsatisfactory curative …

Serum untargeted metabolomics reveal potential biomarkers of progression of diabetic retinopathy in Asians

Z Wang, J Tang, E Jin, Y Zhong, L Zhang… - Frontiers in Molecular …, 2022 - frontiersin.org
Purpose: To reveal molecular mechanisms of diabetic retinopathy (DR) in Asians and
facilitate the identification of new therapeutic targets through untargeted metabolomics. To …

Integrated analysis of metabolomics and lipidomics in plasma of T2DM patients with diabetic retinopathy

C Ding, N Wang, Z Wang, W Yue, B Li, J Zeng… - Pharmaceutics, 2022 - mdpi.com
Diabetic retinopathy (DR) is a major cause of blindness worldwide and may be non-
proliferative (NPDR) or proliferative (PDR). To investigate the metabolomic and lipidomic …

Plasma metabolomic profiling of proliferative diabetic retinopathy

XR Zhu, F Yang, J Lu, H Zhang, R Sun, JB Zhou… - Nutrition & …, 2019 - Springer
Background Proliferative diabetic retinopathy (PDR), a sight-threatening retinopathy, is the
leading cause of irreversible blindness in adults. Despite strict control of systemic risk …

Untargeted multiomics approach coupling lipidomics and metabolomics profiling reveals new insights in diabetic retinopathy

P Ancel, JC Martin, E Doukbi, M Houssays… - International Journal of …, 2023 - mdpi.com
Diabetic retinopathy (DR) is a microvascular complication of diabetes mellitus (DM) which is
the main cause of vision loss in the working-age population. Currently known risk factors …

Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes

Y Tomofuji, K Suzuki, T Kishikawa, N Shojima… - Communications …, 2023 - nature.com
Background Type 2 diabetes is a common disease around the world and its major
complications are diabetic retinopathy (DR) and diabetic kidney disease (DKD). Persons …

High-coverage serum metabolomics reveals metabolic pathway dysregulation in diabetic retinopathy: A propensity score-matched study

C Guo, D Jiang, Y Xu, F Peng, S Zhao, H Li… - Frontiers in Molecular …, 2022 - frontiersin.org
Background: Diabetic retinopathy (DR) is a major diabetes-related disease linked to
metabolism. However, the cognition of metabolic pathway alterations in DR remains scarce …

Plasma metabolomics reveals metabolic profiling for diabetic retinopathy and disease progression

Y Sun, H Zou, X Li, S Xu, C Liu - Frontiers in Endocrinology, 2021 - frontiersin.org
Backgrounds Diabetic retinopathy (DR), the main retinal vascular complication of DM, is the
leading cause of visual impairment and blindness among working-age people worldwide …

[HTML][HTML] Metabolomics in diabetic retinopathy: a systematic review

XW Hou, Y Wang, CW Pan - Investigative ophthalmology & …, 2021 - tvst.arvojournals.org
Purpose: Diabetic retinopathy (DR), a common microvascular complication of diabetes, is
the leading cause of acquired blindness in the working-age population. Individuals with …