Despite the success of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines, there remains a need for more prevention and treatment options for individuals …
CEZ Chan, SGK Seah, DH Chye, S Massey, M Torres… - PLoS …, 2021 - journals.plos.org
Although SARS-CoV-2-neutralizing antibodies are promising therapeutics against COVID- 19, little is known about their mechanism (s) of action or effective dosing windows. We report …
There is an urgent need for effective therapeutic interventions against SARS-CoV-2, including new variants that continue to arise. Neutralizing monoclonal antibodies have …
The severe acute respiratory syndrome (SARS-CoV-2), a newly emerging of coronavirus, continues to infect humans in the absence of a viable treatment. Neutralizing antibodies that …
W Tai, K Yang, Y Liu, R Li, S Feng, B Chai… - Nature …, 2023 - nature.com
The respiratory system, especially the lung, is the key site of pathological injury induced by SARS-CoV-2 infection. Given the low feasibility of targeted delivery of antibodies into the …
SARS-CoV-2 poses a public health threat for which therapeutic agents are urgently needed. Herein, we report that high-throughput microfluidic screening of antigen-specific B-cells led …
X Zhang, H Zhang, T Li, S Chen, F Luo… - Signal transduction and …, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still rapidly spreading worldwide. Many drugs and vaccines have been approved for clinical use show efficacy in …
PJ Halfmann, A Castro, K Loeffler… - Bioengineering & …, 2021 - Wiley Online Library
The persistence of the global severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐ 2) pandemic has brought to the forefront the need for safe and effective vaccination …
D Li, T Li, H Cai, H Yao, B Zhou, Y Zhao, W Qin… - 2020 - pesquisa.bvsalud.org
ABSTRACT SARS-CoV-2, the causative agent of COVID-191, recognizes host cells by attaching its receptor-binding domain (RBD) to the host receptor ACE22-7. Neutralizing …